Product Overview
Malegra FXT is a dual-action medication designed to simultaneously address two prevalent male sexual health conditions. This innovative tablet combines Sildenafil 100 mg and Fluoxetine 40 mg to effectively manage both erectile dysfunction (ED) and premature ejaculation (PE), offering men a convenient and comprehensive treatment solution for improved sexual performance and enhanced intimate experiences.
Therapeutic Applications
Malegra FXT is clinically indicated for:
- Erectile Dysfunction Management: Facilitates the attainment and maintenance of sufficient penile rigidity for satisfactory sexual intercourse through enhanced blood circulation.
- Premature Ejaculation Control: Effectively extends intravaginal ejaculatory latency time, thereby improving sexual endurance and partner satisfaction.
Administration Guidelines
For optimal results with Malegra FXT:
- Ingest one tablet whole with adequate water intake
- Administer 30-60 minutes prior to anticipated sexual activity
- Refrain from concurrent alcohol consumption or heavy meals
- Note that sexual arousal remains necessary for therapeutic effect
Mechanism of Action
Malegra FXT exerts its pharmacological effects through synergistic mechanisms:
- Sildenafil Component: As a PDE5 inhibitor, it enhances nitric oxide-mediated vasodilation in the corpus cavernosum, promoting penile blood flow and tumescence.
- Fluoxetine Component: This SSRI modulates central serotonin neurotransmission, increasing ejaculatory control through 5-HT receptor activation.
Dosage Protocol
The standard therapeutic regimen consists of one tablet (Sildenafil 100 mg/Fluoxetine 40 mg) administered orally once daily, preferably 30-60 minutes before sexual engagement. Maximum daily dosage should not be exceeded without medical supervision.
Therapeutic Advantages
- Dual-action formulation addressing both ED and PE
- Facilitates adequate penile erection for sexual performance
- Significantly prolongs ejaculatory latency time
- Improves overall sexual satisfaction metrics
- Simplified treatment regimen in single-tablet form
Adverse Effects
Common adverse reactions may include:
- Cephalalgia (headache)
- Gastrointestinal discomfort
- Vertigo or lightheadedness
- Facial erythema (flushing)
- Xerostomia (dry mouth)
These transient effects typically resolve without intervention. Persistent symptoms warrant medical consultation.
Precautions
Important considerations include potential pharmacokinetic interactions with:
- Organic nitrates (risk of profound hypotension)
- Alpha-adrenergic antagonists (additive blood pressure effects)
- CYP3A4 inhibitors/inducers (may alter drug metabolism)
Patients with cardiovascular, hepatic, renal, or hematological comorbidities require physician evaluation prior to use.
Contraindications
Malegra FXT is contraindicated in:
- Hypersensitivity to active constituents or excipients
- Concurrent nitrate therapy
- Severe hepatic impairment (Child-Pugh C)
- Women and pediatric populations
Storage Conditions
Maintain at controlled room temperature (15-30°C) in original packaging. Protect from moisture and direct sunlight. Keep securely stored to prevent accidental ingestion by children or pets.
Medical Disclaimer
This information is provided for educational purposes only and represents expert-reviewed pharmacological data. It does not constitute medical advice nor replace professional clinical judgment. Healthcare providers should be consulted for personalized treatment recommendations, complete safety information, and comprehensive drug interaction profiles. This content aims to supplement, not substitute, the essential physician-patient relationship.
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