Centrex

Product Description:

Centrex is an antiviral medication containing Valacyclovir as its active ingredient. This prescription drug is specifically formulated to treat infections caused by the herpes simplex virus, including genital herpes, oral herpes (cold sores), and herpes zoster (shingles).

Uses:

Centrex is indicated for:

• Treatment of genital herpes outbreaks
• Management of cold sores (herpes labialis)
• Treatment of shingles (herpes zoster)
• Prevention of recurrent herpes infections

It may also be prescribed off-label for other viral infections at your doctor’s discretion.

How to Use:

1. Take Centrex exactly as directed by your physician
2. Swallow tablets whole with water – do not crush, chew, or split
3. May be taken with or without food (follow your doctor’s recommendation)
4. Complete the entire prescribed course, even if symptoms improve
5. For swallowing difficulties, consult your healthcare provider about alternative formulations

Mechanism of Action:

Centrex works through its active component Valacyclovir, which converts to acyclovir in the body. This active metabolite:

• Inhibits viral DNA polymerase
• Blocks viral DNA replication
• Prevents viral spread to healthy cells

This action reduces viral load and helps control infection symptoms.

Benefits:

Centrex offers multiple therapeutic advantages:

• Shortens healing time of herpes lesions
• Decreases pain and discomfort
• Reduces frequency of outbreaks (with suppressive therapy)
• Lowers risk of viral transmission
• Improves overall symptom management

Common Side Effects:

While generally well-tolerated, some patients may experience:

• Gastrointestinal upset (nausea, abdominal discomfort)
• Headache
• Dizziness
• Mild fatigue
• Occasional diarrhea

These effects are typically transient. Consult your doctor if they persist or worsen.

Dosage Guidelines:

Dosage varies based on:

• Type and severity of infection
• Patient’s kidney function
• Treatment purpose (acute vs. suppressive therapy)

Always follow your physician’s specific dosing instructions.

Important Precautions:

Before starting Centrex:

• Disclose all medical conditions, especially kidney disease or immune disorders
• Provide complete medication history, including supplements
• Note: Centrex manages symptoms but doesn’t eliminate the herpes virus
• Exercise caution when driving or operating machinery due to potential dizziness
• Maintain adequate hydration during treatment

Storage Information:

Proper storage ensures medication effectiveness:

• Store at controlled room temperature (15-30°C)
• Protect from moisture and direct sunlight
• Keep in original packaging
• Store securely away from children and pets
• Dispose of expired medication properly