Pearl Cream

Product Overview

Perlice Cream is a medicated topical solution formulated with Permethrin as its active ingredient. Designed to combat head lice infestations, it effectively eradicates both adult lice and their eggs (nits) from the scalp and hair. This treatment offers a safe, clinically-proven approach to relieving the itching and discomfort caused by these parasitic insects, providing a convenient solution for affected individuals.

Indications

Perlice Cream is indicated for the treatment of head lice (Pediculus humanus capitis) in patients aged 2 months and older. The medication is effective against both active infestations and as a prophylactic measure following exposure to lice. Head lice are ectoparasites that feed on human blood, causing scalp irritation and intense itching. Permethrin’s insecticidal properties target the lice’s nervous system, ensuring comprehensive eradication.

Application Instructions

1. Wash hair with regular shampoo and towel-dry until damp
2. Apply sufficient cream to completely saturate scalp and hair
3. Focus application on areas behind ears and nape of neck
4. Massage thoroughly to ensure even distribution
5. Leave on for 10 minutes (do not exceed recommended duration)
6. Rinse thoroughly with warm water
7. Repeat treatment after 7-10 days if live lice persist

Mechanism of Action

Permethrin, a synthetic pyrethroid compound, exerts its pediculicidal effect through:
– Disruption of sodium channel function in lice nervous systems
– Paralysis of insect neuromuscular activity
– Prevention of nit hatching
– Residual protection against reinfestation

This dual action ensures elimination of existing parasites while providing ongoing protection during the treatment period.

Dosage Guidelines

Age Group | Application Frequency | Treatment Duration
———|———————|——————
≥2 months | Single application | 10 minutes
All ages | Repeat after 7-10 days if needed | As directed

Therapeutic Advantages

– Clinically proven efficacy (≥95% success rate)
– Minimal systemic absorption
– Non-greasy formulation
– Suitable for all hair types
– Single-application protocol
– Prevents lice resistance development

Potential Adverse Effects

Most common (≤5% of users):
– Transient scalp tingling
– Mild erythema
– Temporary pruritus
– Dry scalp sensation

Precautions

Contraindications:
– Hypersensitivity to pyrethroids
– Pre-existing scalp lesions
– Concurrent use with other pediculicides

Special Populations:
– Pregnancy Category B
– Lactation: Consult physician
– Elderly: No special requirements

Storage Conditions

Parameter | Requirement
———-|————
Temperature | 15-30°C (59-86°F)
Humidity | <60% RH Light Protection | Required Shelf Life | 24 months unopened Medical Disclaimer

The information provided herein represents expert-reviewed pharmacological data intended for educational purposes only. This content does not constitute medical advice nor replace professional clinical judgment. Healthcare providers should be consulted for:
– Individual treatment plans
– Management of adverse reactions
– Drug interaction assessments
– Special population considerations

Patients are advised to:
– Discontinue use if severe irritation occurs
– Seek medical attention for treatment failures
– Complete full course as prescribed
– Implement environmental decontamination measures