Xarelto 20

Product Overview

Xarelto is a prescription medication containing the active ingredient Rivaroxaban, formulated as film-coated tablets. As a direct oral anticoagulant (DOAC), it belongs to the class of blood-thinning medications. Xarelto is clinically proven to prevent stroke in patients with atrial fibrillation, treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE), and reduce the risk of blood clots following knee or hip replacement surgery.

Medical Applications

Xarelto is indicated for:

• Stroke and systemic embolism prevention in nonvalvular atrial fibrillation patients
• Acute treatment and secondary prevention of DVT and PE
• Prophylaxis against venous thromboembolism in orthopedic surgery patients

Administration Guidelines

Take Xarelto tablets whole with water, either with or without meals. Strictly adhere to your physician’s prescribed dosage and treatment duration. The tablet should be swallowed intact—do not crush, chew, or split. If a dose is missed, take it immediately when remembered unless it’s nearly time for the next dose. Never take a double dose to compensate for a missed one.

Mechanism of Action

Rivaroxaban selectively inhibits Factor Xa, a crucial enzyme in the coagulation cascade. By blocking this key component, Xarelto prevents thrombin generation and subsequent fibrin clot formation. This targeted action effectively reduces thrombotic events while maintaining predictable anticoagulation without routine monitoring.

Dosing Protocol

Xarelto dosing is individualized based on:

• Indication being treated
• Renal function status
• Concomitant medications
• Patient-specific risk factors

Most indications require once-daily dosing. Your healthcare provider will determine the optimal regimen after comprehensive evaluation.

Therapeutic Advantages

Key benefits include:

• Superior stroke prevention in atrial fibrillation compared to warfarin
• Single-drug solution for DVT/PE treatment and prevention
• Effective thromboprophylaxis in major orthopedic surgeries
• Fixed dosing without routine INR monitoring
• Minimal food and drug interactions compared to traditional anticoagulants

Adverse Effects

Common adverse reactions may include:

• Increased bleeding tendency (most significant risk)
• Hematoma formation
• Gastrointestinal discomfort
• Neurological symptoms (dizziness, headache)

Seek immediate medical attention for signs of serious bleeding (uncontrolled epistaxis, hematuria, melena, or hematemesis).

Important Precautions

Contraindications include:

• Active pathological bleeding
• Severe hepatic impairment
• Hypersensitivity to rivaroxaban

Special caution required for:

• Elderly patients
• Renal impairment cases
• Concomitant antiplatelet/NSAID use

Storage Conditions

Maintain at controlled room temperature (20-25°C) in original packaging. Protect from moisture and excessive heat. Keep securely closed and out of children’s reach. Discard any expired medication properly.

Medical Disclaimer

While we strive to provide accurate, physician-reviewed information, this content should not replace professional medical advice. The information presented may not encompass all potential adverse effects, contraindications, or drug interactions. Always consult your healthcare provider for personalized guidance regarding medical conditions and treatments. This resource is intended to complement, not substitute, the crucial relationship between patients and their physicians.