Arachitol 6L Injection

Product Overview

Arachitol 6L Injection is a vitamin D3 supplement containing cholecalciferol (600,000 IU) in an injectable ampoule formulation. This high-potency vitamin D preparation is designed to address deficiencies and support physiological functions where oral supplementation may be inadequate. As a fat-soluble vitamin, D3 plays essential roles in calcium homeostasis, bone metabolism, and immune system regulation.

Therapeutic Indications

This injection is indicated for:
– Correction and prevention of vitamin D deficiency
– Management of bone disorders including osteoporosis and osteomalacia
– Treatment of nutritional rickets
– Adjunctive therapy in hypoparathyroidism
– Support for patients with malabsorption syndromes
– Renal osteodystrophy in chronic kidney disease

Administration Guidelines

For professional medical use only:
1. Administer via deep intramuscular injection
2. Strict aseptic technique must be observed
3. Dosage regimen determined by:
– Baseline 25-hydroxyvitamin D levels
– Clinical presentation
– Patient demographics
– Comorbid conditions
4. Not for self-administration

Mechanism of Action

Cholecalciferol undergoes hepatic 25-hydroxylation and renal 1α-hydroxylation to form active calcitriol (1,25-dihydroxyvitamin D3), which:
– Enhances intestinal calcium and phosphate absorption
– Promotes bone mineralization
– Modulates parathyroid hormone secretion
– Supports neuromuscular function
– Regulates immune responses

Dosing Protocol

Standard adult dose: 600,000 IU as single intramuscular injection
Pediatric dose: As clinically indicated based on body weight
Maintenance therapy: May require repeat dosing at intervals determined by monitoring serum vitamin D and calcium levels

Therapeutic Advantages

• Rapid correction of vitamin D deficiency
• Bypasses gastrointestinal absorption limitations
• Ensures compliance with single-dose regimen
• Supports musculoskeletal health
• May benefit immune modulation

Adverse Reactions

Most common:
– Injection site discomfort
– Transient hypercalcemia
– Mild gastrointestinal disturbances

Rare but serious:
– Vitamin D toxicity
– Allergic reactions
– Nephrocalcinosis (with prolonged excessive use)

Precautions

Contraindicated in:
– Hypervitaminosis D
– Hypercalcemia
– Renal calculi with hypercalciuria

Special populations:
– Pregnancy/lactation: Risk-benefit assessment required
– Renal impairment: Dose adjustment may be necessary
– Concurrent cardiac glycosides: Increased risk of arrhythmias

Storage Conditions

– Maintain at controlled room temperature (15-30°C)
– Protect from light
– Do not freeze
– Keep in original packaging
– Store in secure location

Medical Disclaimer

This information serves educational purposes only and does not constitute medical advice. Healthcare providers should make treatment decisions based on individual patient assessments. Product information may be updated – refer to current prescribing information for complete details. Always consult qualified medical professionals regarding health conditions and treatments.