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Product Overview

Mefque is a prescription antimalarial medication containing Mefloquine (250mg) in tablet form. It is used for both prevention and treatment of malaria infections caused by Plasmodium falciparum and Plasmodium vivax parasites. This medication is particularly recommended for travelers to malaria-endemic regions. The active component, Mefloquine, works by inhibiting parasite development in red blood cells, effectively stopping malaria progression.

Uses

Mefque is indicated for:
– Malaria prevention in travelers to endemic areas
– Treatment of acute malaria infections
– Prophylaxis for individuals at occupational risk
– Protection for residents of malaria-prone regions

Note: Mefque should only be used under medical supervision for approved malaria indications.

How to Use

For prevention:
– Begin 1-2 weeks before travel
– Take weekly during exposure
– Continue for 4 weeks post-exposure

For treatment:
– Follow physician-prescribed regimen
– Dosage varies by infection severity and patient factors

Administration tips:
– Take with food or milk
– Swallow tablets whole
– Maintain consistent dosing schedule

How it Works

Mefque’s active component, Mefloquine, is a schizonticidal agent that:
– Disrupts parasite mitochondrial function
– Inhibits hemozoin formation
– Accumulates toxic heme products
– Targets multiple parasite life stages
– Prevents erythrocytic development

Dosage and Administration

Standard dosing guidelines:
– Prophylaxis: 250mg weekly
– Treatment: Initial 1250mg followed by maintenance
– Pediatric dosing by weight

Important notes:
– Complete full course
– Never crush tablets
– Maintain weekly schedule for prophylaxis
– Adjust for renal/hepatic impairment

Benefits

• Proven efficacy against resistant strains
• Weekly dosing convenience
• Comprehensive parasite lifecycle coverage
• Established safety profile
• Dual prevention/treatment indication

Common Side Effects

Frequent (≥1%):
– Gastrointestinal disturbances
– Dizziness/vertigo
– Sleep disorders
– Headache
– Visual disturbances

Serious (report immediately):
– Neuropsychiatric symptoms
– Cardiac arrhythmias
– Severe hypersensitivity
– Convulsions
– Hematologic abnormalities

Warnings

Contraindications:
– History of psychiatric disorders
– Epilepsy/seizure disorders
– Cardiac conduction abnormalities
– Pregnancy (first trimester)
– Mefloquine hypersensitivity

Precautions:
– Monitor for neuropsychiatric effects
– Assess cardiac function
– Review concomitant medications
– Evaluate travel itinerary
– Consider alternative prophylaxis in high-risk patients

Storage Information

Proper storage conditions:
– Temperature: 15-30°C
– Protect from moisture
– Keep in original packaging
– Secure from children/pets
– Check expiration dates
– Dispose properly per regulations

Disclaimer:

This information is provided for educational purposes only and does not constitute medical advice. While we strive for accuracy, this content should not replace professional medical consultation. Healthcare providers should be consulted for:
– Individual treatment plans
– Complete safety information
– Potential drug interactions
– Specific health concerns
– Personalized risk assessments

Our goal is to supplement, not replace, the essential relationship between patients and their healthcare providers. Always follow your physician’s guidance regarding medication use.