Cifran OZ

Product Overview

Cifran OZ is a combination medication formulated with Ciprofloxacin (500mg) and Ornidazole (500mg) in tablet form. This dual-action antibiotic and antiprotozoal therapy is designed to combat a wide range of bacterial and parasitic infections. By disrupting the growth and reproduction of harmful microorganisms, Cifran OZ enhances the body’s natural defense mechanisms to effectively clear infections.

Indications

This medication is indicated for treating diverse bacterial infections affecting the urinary tract, respiratory system, gastrointestinal tract, skin/soft tissues, and sexually transmitted diseases. It also demonstrates efficacy against protozoal infections including amoebiasis and giardiasis. Healthcare providers typically prescribe Cifran OZ when infections are suspected to be caused by susceptible pathogens.

Administration Guidelines

For optimal results, swallow Cifran OZ tablets whole with ample water, preferably during meals to minimize potential stomach discomfort. The tablets should not be crushed, chewed, or split. Complete the entire prescribed treatment regimen, even if symptoms subside before completion. Premature discontinuation may lead to treatment failure and promote antibiotic resistance.

Mechanism of Action

Cifran OZ’s therapeutic effect stems from its two active components working synergistically:
– Ciprofloxacin (a fluoroquinolone antibiotic) targets bacterial DNA gyrase and topoisomerase IV enzymes, crucial for microbial DNA processes
– Ornidazole (an antiprotozoal agent) disrupts protozoal DNA structure
This dual mechanism provides comprehensive antimicrobial coverage against both bacterial and protozoal pathogens.

Dosage Protocol

Dosage varies based on infection type/severity, patient characteristics (age, weight, kidney function), and medical assessment. Standard regimen involves twice-daily administration for 5-14 days. Strict adherence to the prescribed treatment duration is crucial for therapeutic success.

Therapeutic Advantages

• Dual-action against bacterial and protozoal infections
• Broad-spectrum antimicrobial efficacy
• Convenient oral tablet formulation
• Prompt therapeutic response
• Generally favorable safety profile

Potential Adverse Effects

Common but typically transient side effects may include:
– Gastrointestinal disturbances (nausea, vomiting, diarrhea, abdominal discomfort)
– Neurological symptoms (headache, dizziness)
– Taste alterations
Most reactions are mild and self-limiting. Consult your physician if symptoms persist or intensify.

Precautions

Exercise caution in patients with:
– Hypersensitivity to fluoroquinolones, nitroimidazoles, or formulation components
– History of tendon disorders (risk of tendon rupture)
– Neurological conditions (potential peripheral neuropathy risk)
– Clostridium difficile infection predisposition
Pregnancy/lactation use requires careful risk-benefit evaluation by a healthcare professional.

Storage Conditions

Maintain at controlled room temperature in a dry environment, protected from light and moisture. Keep securely stored away from children and pets. Properly dispose of expired or unused medication following local pharmaceutical waste guidelines.

Disclaimer:

This information is intended to provide accurate, expert-reviewed drug knowledge but should not replace professional medical advice. The content serves educational purposes only and may not encompass all potential side effects, interactions, or contraindications. Always consult your healthcare provider for personalized guidance regarding medical conditions and treatments. This information aims to complement, not substitute, the crucial doctor-patient relationship.