Alphadol

Product Overview

Alphadol is a pharmaceutical preparation containing Alfacalcidol as its active ingredient, presented in soft gelatin capsules. Alfacalcidol is a synthetic analog of Vitamin D3 that plays a vital role in regulating calcium and phosphate metabolism, supporting bone health and physiological functions. These capsules are formulated for oral administration, offering an effective solution for individuals with Vitamin D deficiency or those requiring therapeutic supplementation.

Indications

Alphadol is indicated for the management of Vitamin D deficiency and related disorders including osteoporosis, osteomalacia, and hypocalcemia. It aids in maintaining proper calcium and phosphate balance, thereby promoting bone mineralization. Furthermore, Alphadol is utilized in patients with chronic kidney disease to support renal function and prevent bone disorders associated with long-term dialysis.

Administration

Alphadol capsules should be taken orally with water, preferably with meals to optimize absorption and reduce gastrointestinal irritation. The capsule must be swallowed whole—do not crush, chew, or open it. Adhere strictly to the prescribed dosage regimen. Avoid self-adjusting the dose or prolonging treatment without medical advice.

Mechanism of Action

The active component, Alfacalcidol, undergoes metabolic conversion to calcitriol (the active form of Vitamin D3) in the body. Calcitriol enhances intestinal absorption of calcium and phosphate, facilitates renal calcium reabsorption, and modulates bone resorption to maintain mineral homeostasis. This mechanism ensures proper bone formation and skeletal integrity.

Dosage Guidelines

The appropriate dosage of Alphadol is determined by factors such as age, clinical condition, and therapeutic response. Typically administered once daily, dosage adjustments may be required based on periodic monitoring of serum calcium and Vitamin D levels to ensure efficacy and safety.

Therapeutic Benefits

• Promotes bone mineralization and strength
• Corrects Vitamin D deficiency
• Optimizes calcium and phosphate metabolism
• Reduces risk of osteoporotic fractures
• Supports renal health in chronic kidney disease

Adverse Effects

Common adverse reactions may include nausea, constipation, headache, and muscle weakness. These symptoms are generally mild and self-limiting. Consult your healthcare provider if side effects persist or intensify.

Precautions

Therapy with Alphadol requires vigilance for potential hypercalcemia or hyperphosphatemia, particularly in renal impairment patients. Regular serum calcium and phosphate monitoring is essential to mitigate risks. Concurrent use of other Vitamin D or calcium supplements should be avoided unless directed by a physician.

Contraindications

Exercise caution in patients with a history of hypercalcemia, hypercalciuria, or Vitamin D toxicity. Disclose all known allergies or sensitivities to your healthcare provider prior to initiating treatment.

Storage Conditions

Store Alphadol capsules at controlled room temperature, protected from moisture and direct heat. Keep out of reach of children. Discard expired or unused medication in accordance with local disposal guidelines.

Disclaimer:

This information is intended for educational purposes and is derived from expert-reviewed sources. It is not a substitute for professional medical advice. Consult your physician for personalized guidance regarding diagnoses, treatments, or potential drug interactions. This content aims to complement, not replace, the patient-doctor relationship.