Product Overview
Baclof Liquid is a muscle relaxant medication containing the active ingredient Baclofen. This oral solution formulation is designed for convenient administration and precise dosing.
Therapeutic Applications
This medication is primarily indicated for managing muscle spasticity in patients with:
- Multiple sclerosis
- Spinal cord injuries
- Cerebral palsy
It effectively reduces muscle stiffness and improves functional mobility by targeting the central nervous system.
Administration Guidelines
- Shake the suspension thoroughly before each use
- Measure the prescribed dose using the provided calibrated device
- May be diluted with water or juice if preferred
- Administer immediately after preparation
Note: Never use household spoons for measurement.
Mechanism of Action
Baclofen functions as a selective GABA-B receptor agonist in the spinal cord. This pharmacological action:
- Potentiates inhibitory GABAergic neurotransmission
- Reduces excitatory neurotransmitter release
- Decreases monosynaptic and polysynaptic reflex activity
The net effect is significant reduction in muscle hypertonia and spasticity.
Dosing Considerations
Therapeutic dosing requires individualization based on:
- Patient’s clinical response
- Underlying condition severity
- Renal function status
- Concurrent medications
Always adhere to your physician’s prescribed regimen.
Therapeutic Advantages
- Effective spasticity management
- Enhanced range of motion
- Improved activities of daily living
- Pediatric-friendly formulation
- Flexible dosing options
Adverse Effects
Most common treatment-emergent effects include:
- Somnolence (35-45%)
- Dizziness (15-25%)
- Asthenia (10-15%)
- Gastrointestinal discomfort (5-10%)
These typically diminish with continued therapy.
Important Safety Information
Contraindications:
- Hypersensitivity to baclofen
- Severe renal impairment
Precautions:
- Gradual dose titration required
- Monitor for CNS depression
- Caution in elderly patients
- Abrupt discontinuation may precipitate withdrawal syndrome
Storage Requirements
- Maintain at 20-25°C (68-77°F)
- Protect from light exposure
- Ensure tight container closure
- Discard after expiration date
Medical Disclaimer
The content provided is for educational purposes only and should not replace professional medical advice. While we strive for accuracy, this information:
- Does not encompass all potential interactions
- May not reflect current therapeutic guidelines
- Should be verified with prescribing information
Always consult your healthcare provider regarding any medical concerns or treatment decisions.
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