Concor Cor

Product Overview

Concor Cor is a cardiovascular medication containing the active pharmaceutical ingredient Bisoprolol. As a selective beta-1 adrenergic receptor blocker, it inhibits the effects of endogenous catecholamines like epinephrine on cardiac and vascular tissues.

Therapeutic Indications

Concor Cor is indicated for the management of:

• Essential hypertension (high blood pressure)
• Chronic stable angina pectoris (chest pain)
• Chronic heart failure (as part of a comprehensive treatment regimen)

Administration Guidelines

For optimal therapeutic outcomes:

1. Take orally once daily, preferably at the same time each day
2. May be administered with or without food
3. Swallow tablets whole with water
4. Adhere strictly to prescribed dosage regimen

Important: Abrupt discontinuation may precipitate rebound hypertension or angina exacerbation. Always consult your physician before making any changes to your medication schedule.

Mechanism of Action

Bisoprolol, the pharmacologically active component of Concor Cor, exerts its therapeutic effects through:

• Competitive β1-adrenergic receptor antagonism
• Reduction of sympathetic nervous system activity
• Negative chronotropic and inotropic effects

This results in decreased myocardial oxygen demand, improved coronary perfusion, and reduced peripheral vascular resistance.

Dosage Protocol

Therapeutic dosing is individualized based on:

• Clinical indication
• Patient response
• Renal/hepatic function
• Concomitant medications

Typical maintenance doses range from 2.5 mg to 10 mg daily. Titration should be performed under medical supervision.

Therapeutic Benefits

Clinical advantages include:

• Significant reduction in systolic and diastolic blood pressure
• Decreased frequency and severity of anginal episodes
• Improved cardiac output in heart failure patients
• Reduced cardiovascular mortality

Adverse Effects

Commonly reported reactions (incidence >1%):

• Central nervous system: Fatigue, dizziness, headache
• Cardiovascular: Bradycardia, hypotension
• Gastrointestinal: Nausea, diarrhea

Most adverse effects are dose-dependent and typically diminish with continued therapy.

Important Precautions

Contraindications:

• Acute decompensated heart failure
• Second- or third-degree AV block (without pacemaker)
• Cardiogenic shock
• Severe bradycardia (<50 bpm)

Drug Interactions:
Monitor closely with:

• Calcium channel blockers
• Antiarrhythmics
• Insulin/oral hypoglycemics

Storage Conditions

Maintain product integrity by:

• Storing at 15-30°C
• Protecting from moisture and light
• Keeping in original packaging

Medical Disclaimer

This information is provided for educational purposes only and does not constitute medical advice. While we strive for accuracy, this content:

• Is not exhaustive
• May not reflect recent developments
• Should not replace professional medical consultation

Always consult your healthcare provider regarding:

• Diagnosis
• Treatment options
• Potential drug interactions
• Adverse effect management

This information supplements but does not replace the physician-patient relationship.