Glybovin

Product Overview

Glybovin is an oral antidiabetic medication containing Glibenclamide 5 mg as its active pharmaceutical ingredient.

Therapeutic Indications

Glybovin is indicated for the management of type 2 diabetes mellitus in adult patients when adequate glycemic control cannot be achieved through diet and exercise alone.

Mechanism of Action

The active component Glibenclamide belongs to the sulfonylurea class of antidiabetic agents. It stimulates insulin secretion from pancreatic beta cells by binding to specific ATP-sensitive potassium channels, thereby enhancing glucose-dependent insulin release.

Dosage and Administration

The dosage should be individualized based on glycemic response. Typically:

• Initial dose: 2.5-5 mg once daily
• Maintenance dose: May be increased gradually up to 15 mg daily

Administer with the first main meal of the day. Tablets should be swallowed whole with water.

Therapeutic Benefits

Glybovin provides:

• Effective glycemic control in type 2 diabetes
• Convenient once-daily dosing regimen
• Reduction in diabetes-related complications

Adverse Effects

Common adverse reactions may include:

• Hypoglycemia (most frequent)
• Gastrointestinal disturbances (nausea, dyspepsia)
• Dermatological reactions (rash, pruritus)
• Mild weight gain

Precautions and Warnings

Important safety information:

• Contraindicated in type 1 diabetes and diabetic ketoacidosis
• Avoid concurrent alcohol consumption due to disulfiram-like reaction risk
• Use with caution in hepatic or renal impairment
• Not recommended during pregnancy/lactation
• Increased hypoglycemia risk in elderly patients

Storage Conditions

Store at controlled room temperature (15-30°C) in original packaging. Protect from moisture and light. Keep out of reach of children.

Medical Disclaimer:

The information provided is intended for healthcare professionals and educated patients. This summary does not encompass all potential drug interactions, contraindications, or adverse effects. Always consult your prescribing physician before initiating or modifying any treatment regimen. The content aims to supplement, not replace, professional medical judgment.