Itrotab

Product Overview

Itrotab is an antifungal medication containing Itraconazole as its active ingredient. As a member of the triazole derivatives class, it effectively treats various fungal infections affecting the lungs, mouth, throat, and nails. The medication works by blocking ergosterol production, a vital component of fungal cell membranes, which prevents fungal growth and reproduction. Itrotab is formulated as oral tablets for convenient administration.

Uses

Itrotab is prescribed for fungal infections caused by susceptible fungal strains including Aspergillus, Blastomyces, Candida, Coccidioides, and Histoplasma. It effectively treats pulmonary aspergillosis (lung infections), oropharyngeal and esophageal candidiasis (mouth and throat infections), and onychomycosis (nail infections). Additionally, it serves as a preventive measure against fungal infections in immunocompromised individuals, including HIV/AIDS patients and those undergoing chemotherapy.

How to Use

For optimal absorption and reduced gastrointestinal discomfort, take Itrotab tablets with a full glass of water during meals. The prescribed dosage and treatment duration vary based on infection type, severity, and individual patient factors like age, weight, and health status. Complete the entire treatment course as directed by your healthcare provider, even if symptoms subside before finishing the medication.

How it Works

Itrotab’s mechanism of action involves inhibiting the fungal enzyme lanosterol 14-alpha-demethylase, crucial for ergosterol synthesis. This disruption compromises fungal cell membrane integrity, causing cellular content leakage and eventual fungal cell death. The medication selectively targets fungal cells without affecting mammalian cells, making it an effective antifungal treatment.

Dosage and Administration

Dosage varies according to infection type and severity. Standard adult dosing ranges from 100-200 mg once or twice daily. For onychomycosis treatment, a pulsed regimen of 200 mg twice daily for one week per month is common. Treatment duration may extend from several days to months, depending on therapeutic response and infection recurrence.

Benefits

Itrotab offers several advantages:
• High effectiveness against diverse fungal infections, including resistant strains
• Convenient oral administration for home treatment
• Broad-spectrum antifungal coverage for multiple infection types
• Generally good patient tolerance

Common Side Effects

Patients may experience:
• Gastrointestinal issues (nausea, vomiting, diarrhea, abdominal pain)
• Headache or dizziness
• Skin rashes
• Mild liver enzyme elevations

Most side effects are temporary and mild-to-moderate in severity. However, seek medical attention for serious reactions including allergic responses, liver dysfunction, or cardiac rhythm disturbances.

Warnings

Exercise caution when prescribing Itrotab to patients with:
• Liver impairment
• Cardiac conditions
• Electrolyte imbalances

Significant drug interactions may occur with:
• Cisapride
• Dofetilide
• Quinidine
• Pimozide

Contraindications include:
• Pregnancy
• Breastfeeding
• Concurrent alcohol consumption (due to increased hepatotoxicity risk)

Storage Information

Store Itrotab tablets:
• At controlled room temperature (20°C-25°C/68°F-77°F)
• In a dry location away from heat and moisture
• Out of children’s and pets’ reach
• Not in humid areas like bathrooms or near sinks

Properly dispose of expired or unused medication according to local regulations.

Disclaimer:

While we strive to provide accurate, expert-reviewed information, this content should not replace professional medical advice. The information presented here serves educational purposes only and may not include all possible side effects, drug interactions, warnings, or precautions. Always consult your healthcare provider regarding any medical condition or treatment. Our goal is to supplement, not replace, the crucial doctor-patient relationship.