Listril Plus

✅ Controls high blood pressure
✅ Reduces risk of stroke
✅ Prevents heart attacks
✅ Enhances kidney protection
✅ Improves cardiovascular health

Listril Plus contains Lisinopril and hydrochlorothiazide

Listril Plus Tablet is prescribed for managing hypertension (high blood pressure). This combination medication effectively controls blood pressure when monotherapy proves insufficient. It helps prevent potential cardiovascular complications like heart attacks and strokes.

For optimal results, take Listril Plus Tablet in the morning, with or without food, to minimize nighttime urination. Continue treatment as directed by your physician, even if asymptomatic, as hypertension often presents no noticeable symptoms. Discontinuing medication without medical advice may worsen your condition. Complement treatment with regular exercise, weight management, and a balanced diet for better blood pressure control.

Common adverse effects include nausea, altered taste perception, diarrhea, and indigestion. Consult your doctor if these persist or become bothersome. Report any persistent cough or throat irritation. Maintain adequate hydration to alleviate potential muscle weakness, dry mouth, and excessive thirst.

Inform your healthcare provider about any pre-existing liver or kidney conditions before starting treatment. Pregnant or nursing women should seek medical advice prior to use. Disclose all concurrent medications, particularly those for hypertension or cardiac conditions. Regular monitoring of blood pressure, renal function, and electrolyte levels (especially potassium) is recommended to ensure therapeutic efficacy.

THERAPEUTIC INDICATIONS

  • Management of essential hypertension

CLINICAL BENEFITS

In Hypertensive Patients

Listril Plus Tablet exerts its therapeutic effect through dual mechanisms: vasodilation of peripheral blood vessels and diuresis. The medication reduces vascular resistance while promoting sodium and water excretion, thereby lowering blood pressure. This comprehensive action decreases long-term risks of cerebrovascular accidents, myocardial infarction, and renal impairment. While immediate symptomatic relief may not be apparent, consistent adherence to prescribed therapy provides sustained cardiovascular protection. Continue treatment as directed, regardless of symptomatic improvement.

ADVERSE EFFECTS

Most adverse reactions are transient and resolve with continued therapy as the body adapts to medication. Seek medical advice if symptoms persist or cause concern.

Frequently Reported Adverse Reactions

  • Gastrointestinal disturbances (nausea, indigestion)
  • Dysgeusia (taste alteration)
  • Abdominal discomfort
  • Loose stools
  • Cephalalgia
  • Vertigo
  • Asthenia
  • Hypotension
  • Persistent cough
  • Hyperlipidemia
  • Hyperuricemia
  • Electrolyte disturbances
  • Impaired glucose tolerance

ADMINISTRATION GUIDELINES

Administer exactly as prescribed. Swallow the tablet whole with water, without chewing or crushing. While food does not significantly affect absorption, maintaining consistent dosing times enhances therapeutic outcomes.

PHARMACOLOGICAL ACTION

Listril Plus Tablet combines two synergistic antihypertensive agents: Lisinopril (an ACE inhibitor) and hydrochlorothiazide (a thiazide diuretic). Lisinopril inhibits angiotensin-converting enzyme, reducing peripheral vascular resistance and cardiac workload. Hydrochlorothiazide promotes natriuresis and diuresis while gradually inducing vasodilation. This dual mechanism provides comprehensive blood pressure control through complementary pathways.

Important Notice:

This information is provided for educational purposes only and represents expert-reviewed medical content. It should not replace professional medical advice, diagnosis, or treatment. The content may not include all potential adverse effects, drug interactions, or contraindications. Always consult your healthcare provider regarding any medical condition or treatment options. This material is intended to supplement, not substitute, the relationship between patient and physician.
Strength

5 Mg and 12.5 Mg

Quantity

30 Tablet/s, 60 Tablet/s, 90 Tablet/s

Pharma Form

Tablet/s

Manufacturer

Torrent Pharma

Treatment

High blood pressure, Heart failure

Generic Brand

Lisinopril + Hydrochlorothiazide

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