Lodoz

Product Overview

Lodoz is a combination medication containing Bisoprolol Fumarate and Hydrochlorothiazide as active ingredients. This dual-action formulation is prescribed for managing hypertension (high blood pressure). Bisoprolol, a selective beta-blocker, reduces blood pressure by decreasing heart rate and cardiac workload. Hydrochlorothiazide, a thiazide diuretic, promotes fluid elimination through increased urine output, helping remove excess sodium and water from the body.

Uses

Lodoz is indicated for the treatment of hypertension. This medication helps control elevated blood pressure, thereby reducing cardiovascular risks including myocardial infarction, cerebrovascular accidents, and renal complications.

How to Use

Administer Lodoz orally as prescribed, typically once daily. The tablet should be swallowed whole with water, with or without food. Do not crush, chew, or split the tablet. Adhere strictly to your physician’s dosing instructions.

Mechanism of Action

The therapeutic effect of Lodoz is achieved through complementary mechanisms: Bisoprolol competitively blocks beta-adrenergic receptors, inhibiting catecholamine effects on the cardiovascular system, resulting in reduced cardiac output. Hydrochlorothiazide inhibits sodium reabsorption in the distal convoluted tubule, promoting natriuresis and diuresis, which decreases plasma volume and peripheral vascular resistance.

Dosage and Administration

Dosage is individualized based on therapeutic response and patient tolerance. Your healthcare provider will determine the optimal dosing regimen. Maintain strict compliance with prescribed administration schedules.

Therapeutic Benefits

• Effective blood pressure reduction
• Decreased risk of hypertension-related complications including cardiovascular events and renal impairment

Common Adverse Effects

Frequently reported side effects include dizziness, cephalalgia, fatigue, gastrointestinal disturbances (nausea, diarrhea), and polyuria. Persistent or severe reactions warrant medical consultation.

Precautions and Contraindications

• Contraindicated in patients with severe cardiac insufficiency, atrioventricular block, or significant renal dysfunction
• Disclose all concurrent medications including prescription drugs, OTC products, and herbal preparations
• Avoid ethanol consumption due to potential additive hypotensive effects and dehydration risk

Storage Conditions

Maintain Lodoz at controlled room temperature (15-30°C) in a dry environment protected from light. Keep securely stored away from pediatric and pet access.

Disclaimer:

The content provided is intended for informational purposes only and represents expert-reviewed medical information. This material should not substitute professional medical advice, diagnosis, or treatment. The complete profile of potential adverse effects, drug interactions, or contraindications may not be fully described herein. Always consult your healthcare provider regarding any medical condition or therapeutic regimen. This information aims to complement, not replace, the physician-patient relationship.