Product Overview
Neckcin 100 DT is a fast-dissolving tablet formulation containing Azithromycin, a macrolide-class antibiotic. These dispersible tablets are designed for easy administration by dissolving in water, particularly beneficial for patients who experience difficulty swallowing conventional tablets. As a broad-spectrum antibiotic, Azithromycin effectively treats various bacterial infections including respiratory tract infections, dermatological conditions, otitis media, and certain sexually transmitted infections.
Therapeutic Indications
This medication is prescribed for bacterial infections caused by susceptible pathogens. Clinical applications include:
- Respiratory infections (pneumonia, acute bronchitis, sinusitis)
- Dermatological infections (cellulitis, impetigo)
- Genitourinary infections (chlamydia, uncomplicated gonorrhea)
Note: This antibiotic demonstrates no efficacy against viral infections like influenza or common cold.
Administration Guidelines
- Place tablet in 50-100ml of water
- Allow complete dissolution (approximately 2 minutes)
- Stir gently and consume immediately
Administer once daily on an empty stomach (1 hour before or 2 hours after meals) unless otherwise directed. Complete the prescribed course even if symptoms resolve earlier. Tablets should not be chewed or crushed.
Mechanism of Action
Azithromycin exerts bacteriostatic effects by:
- Binding to the 50S ribosomal subunit
- Inhibiting protein synthesis
- Preventing peptide chain elongation
This action results in suppression of bacterial growth across Gram-positive, Gram-negative, atypical, and anaerobic organisms.
Dosage Protocol
Patient Group | Dosage | Duration |
---|---|---|
Adults & Children >45kg | 500mg daily | 3 days |
Pediatric Patients | 10mg/kg daily | 3 days |
Dosage adjustments may be required for hepatic impairment. Always follow medical supervision.
Therapeutic Advantages
- Broad antimicrobial coverage
- Convenient single-daily dosing
- Improved compliance through dispersible formulation
- Favorable safety profile
- Extended post-antibiotic effect
Adverse Effects
Most common (≥1% incidence):
- Gastrointestinal: Nausea, diarrhea, abdominal discomfort
- Neurological: Headache, dizziness
Serious reactions requiring immediate medical attention:
- Hypersensitivity reactions
- Hepatotoxicity
- Cardiac arrhythmias
- Hearing impairment
Precautions
Contraindications include:
- History of macrolide hypersensitivity
- Concurrent use with ergot derivatives
Special precautions for:
- Patients with hepatic/renal impairment
- Those with myasthenia gravis
- Individuals with QT prolongation risk factors
Avoid alcohol consumption during therapy. Exercise caution when operating machinery.
Storage Conditions
- Store below 30°C
- Protect from moisture and light
- Keep in original packaging
- Store out of children’s reach
Properly dispose of expired medication through pharmaceutical take-back programs.
Medical Disclaimer
This information serves educational purposes only and does not constitute medical advice. While we strive for accuracy, this content may not encompass all potential drug interactions, contraindications, or adverse effects. Always consult your healthcare provider for personalized medical guidance. This information supplements but does not replace professional medical judgment or the essential doctor-patient relationship.
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