Product Overview
Nise Gel is a topical analgesic containing Nimesulide, a nonsteroidal anti-inflammatory drug (NSAID). Designed as an easy-to-apply gel formulation, it delivers targeted relief from pain and inflammation associated with musculoskeletal disorders including sprains, strains, and arthritic conditions. The gel format ensures direct application to affected areas, facilitating rapid absorption and quicker onset of therapeutic action.
Uses
This medication is clinically indicated for managing pain and inflammatory symptoms in conditions such as:
– Osteoarthritis and rheumatoid arthritis
– Back pain and musculoskeletal discomfort
– Sports-related injuries
– Soft tissue inflammation
– Minor traumatic injuries (sprains/strains)
The gel formulation provides localized treatment while minimizing systemic exposure.
How to Use
For optimal results:
1. Cleanse and dry the affected area thoroughly
2. Apply a thin, even layer of gel
3. Gently massage until completely absorbed
4. Wash hands post-application
5. Frequency: Typically 3-4 applications daily or as medically advised
Avoid contact with eyes/mucous membranes. Use precisely as prescribed by your healthcare provider.
How it Works
Nimesulide exerts its therapeutic effect through selective inhibition of cyclooxygenase-2 (COX-2) enzyme, thereby suppressing prostaglandin synthesis. This mechanism:
– Reduces localized inflammation
– Alleviates pain at the application site
– Minimizes systemic effects
The topical delivery ensures concentrated action at the affected area without significant whole-body exposure.
Dosage and Administration
Dosing Guidelines:
– Standard: Apply 3-4 times daily
– Quantity: Sufficient to cover affected area (pea-sized amount per 5cm²)
– Duration: As prescribed (typically not exceeding 15 days)
Important Precautions:
– Do not apply to broken/damaged skin
– Avoid occlusive dressings
– Discontinue if irritation occurs
– Medical supervision required for prolonged use
Benefits
Key Advantages:
– Targeted pain relief without oral medication
– Reduced gastrointestinal side effects
– Convenient application
– Rapid absorption
– Suitable for patients with swallowing difficulties
– Can be combined with other analgesics (under medical guidance)
Common Side Effects
Localized reactions may include:
– Transient skin irritation
– Erythema (redness)
– Pruritus (itching)
– Contact dermatitis
These typically resolve spontaneously. Discontinue use if persistent or severe reactions occur and consult your physician.
Warnings
Important Safety Information:
– Contraindicated in NSAID hypersensitivity
– Avoid application near eyes/mucous membranes
– Not recommended for:
– Pregnant/lactating women
– Patients with hepatic impairment
– Children under 12 years
– Caution required in:
– Elderly patients
– Those with renal dysfunction
– Asthma/atopy history
Storage Information
Proper Storage Conditions:
– Temperature: 15-30°C
– Protection: Keep away from light/moisture
– Security: Store out of children’s reach
– Stability: Do not freeze
– Disposal: Follow local regulations for expired products
Disclaimer:
This information is provided for educational purposes only and represents expert-reviewed medical content. It should not:
– Replace professional medical advice
– Be considered exhaustive regarding:
– Potential adverse effects
– Drug interactions
– Contraindications
Always consult your healthcare provider for personalized medical guidance. This content aims to supplement, not substitute, the crucial physician-patient relationship.
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