Oflomac-M Oral Suspension

Product Overview

Oflomac-M Suspension is a dual-action antimicrobial medication combining Ofloxacin and Metronidazole in an oral suspension form. This specialized formulation provides comprehensive treatment against both bacterial and protozoal infections, particularly those affecting the digestive and urinary systems. The suspension format ensures optimal absorption and patient compliance.

Uses

This medication is prescribed for treating:
– Bacterial gastrointestinal infections (including traveler’s diarrhea)
– Protozoal infections (amoebiasis, giardiasis)
– Mixed bacterial-protozoal infections
– Genitourinary tract infections

The dual-active formula effectively combats infection-causing microorganisms while relieving associated symptoms.

How to Use

1. Shake bottle vigorously before each dose
2. Measure prescribed quantity using provided dosing device
3. Administer orally with or without food as directed
4. Complete entire prescribed course, even if symptoms improve
5. Maintain regular dosing intervals for optimal effectiveness

Mechanism of Action

The suspension combines two potent antimicrobial agents:
1. Ofloxacin (fluoroquinolone antibiotic):
– Inhibits bacterial DNA gyrase and topoisomerase IV
– Disrupts DNA replication in susceptible bacteria

2. Metronidazole (nitroimidazole antimicrobial):
– Forms toxic radicals that damage microbial DNA
– Effective against anaerobic bacteria and protozoa

This synergistic action provides broad-spectrum coverage against multiple pathogens.

Dosage Guidelines

Dosage is individualized based on:
– Type and severity of infection
– Patient age and weight
– Renal/hepatic function

Typical regimen:
– Adults: 5-10ml twice daily
– Children: 0.5-1ml/kg/day in divided doses
– Treatment duration: 5-10 days (as prescribed)

Key Advantages

1. Dual antimicrobial coverage in single formulation
2. Suspension allows precise pediatric dosing
3. Enhanced gastrointestinal tolerance
4. Rapid systemic absorption
5. Convenient twice-daily dosing

Potential Side Effects

Common (1-10% of users):
– Gastrointestinal: nausea, mild diarrhea, epigastric discomfort
– Neurological: mild headache, transient dizziness

Rare but serious (report immediately):
– Allergic reactions
– Persistent diarrhea
– Neurological symptoms (tingling, seizures)
– Dark urine or jaundice

Important Precautions

Contraindications:
– Known hypersensitivity to quinolones or nitroimidazoles
– History of tendinitis with quinolones
– Neurological disorders

Special warnings:
– Avoid alcohol during and for 72 hours post-treatment
– May cause dizziness (caution when driving)
– Discontinue if tendon pain/swelling occurs
– Monitor for superinfections

Storage Conditions

1. Store at 15-30°C
2. Protect from light and moisture
3. Keep bottle tightly sealed
4. Do not refrigerate or freeze
5. Discard unused portion after completion of therapy

Medical Disclaimer

This information serves educational purposes only and does not replace professional medical advice. Consult your healthcare provider for:
– Proper diagnosis
– Personalized treatment plans
– Management of side effects
– Drug interaction checks
– Pregnancy/lactation guidance

Always follow your physician’s instructions regarding medication use and report any unusual symptoms promptly.