Oflomac

Product Overview

Oflomac is a pharmaceutical preparation containing the active ingredient Ofloxacin, classified under the fluoroquinolone group of antibiotics. Available in multiple formulations—including oral tablets, ophthalmic drops, and otic drops—Oflomac offers targeted treatment for diverse bacterial infections. It is frequently prescribed for infections affecting the urinary tract, respiratory system, integumentary system (skin), and auditory canal, among others.

Uses

Oflomac is indicated for the management of bacterial infections caused by susceptible microorganisms. Common therapeutic applications include urinary tract infections (UTIs), acute bronchitis, community-acquired pneumonia, dermatological infections, and otitis externa. Its bactericidal action is achieved through inhibition of bacterial DNA gyrase, an enzyme essential for DNA replication, thereby terminating bacterial proliferation.

How to Use

Administration guidelines for Oflomac vary by formulation and clinical indication:
– **Oral tablets**: Swallow whole with water, with or without food, adhering to prescribed dosing schedules.
– **Ophthalmic/otic drops**: Apply as per the labeled instructions or healthcare provider’s guidance.
Complete the entire prescribed course, even if symptoms subside prematurely, to prevent antibiotic resistance and ensure microbial eradication.

Mechanism of Action

Oflomac exerts its antibacterial effect by selectively inhibiting bacterial DNA gyrase (topoisomerase II), disrupting DNA supercoiling and replication. This interference compromises bacterial genomic integrity, leading to cell death. Its targeted action provides efficacy against gram-positive and gram-negative pathogens.

Dosage and Administration

Dosage is individualized based on:
– Infection type and severity
– Patient-specific factors (age, renal function, comorbidities)
Standard regimens include:
– **Oral**: 200–400 mg every 12–24 hours
– **Topical**: 1–2 drops in affected eye/ear every 4–12 hours
Adhere strictly to clinician-prescribed protocols.

Benefits

1. **Rapid symptomatic relief**: Reduces infection-related morbidity promptly.
2. **Broad-spectrum coverage**: Effective against diverse aerobic bacteria.
3. **Formulation flexibility**: Enables site-specific therapy (systemic/localized infections).

Common Side Effects

Frequently reported adverse reactions (typically mild/transient):
– Gastrointestinal: Nausea, diarrhea, dyspepsia
– Neurological: Dizziness, headache
– Dermatological: Rash, pruritus
Discontinue and seek medical advice if effects persist or intensify.

Warnings and Precautions

**Serious risks**:
– Tendinopathy/tendon rupture (higher risk in elderly/corticosteroid users)
– Peripheral neuropathy (irreversible in some cases)
– CNS effects (seizures, insomnia)
**Contraindications/Cautions**:
– History of myasthenia gravis, QT prolongation, or hypersensitivity to quinolones
– Drug interactions (e.g., antacids, warfarin, theophylline) – disclose all concomitant medications.

Storage Conditions

– **Tablets**: Store below 30°C in a dry environment.
– **Drops**: Follow product-specific storage guidelines (e.g., refrigeration after opening).
Dispose of expired/unused medication via approved pharmaceutical waste channels.

Disclaimer:

This content is curated for educational purposes and has undergone medical review. It is not a substitute for professional clinical judgment. Consult a licensed healthcare provider for personalized advice, including comprehensive risk assessments (e.g., side effects, contraindications). This information aims to supplement, not replace, physician-patient dialogue.