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Product Description

Ostat is a pharmaceutical preparation containing Orlistat as its active component, formulated as oral capsules for administration.

Therapeutic Applications

Ostat is indicated for obesity management and weight reduction when used alongside a calorie-controlled diet. It is prescribed for patients with a body mass index (BMI) ≥30 kg/m², or those with BMI ≥27 kg/m² accompanied by obesity-related comorbidities such as diabetes mellitus or hypertension. The drug functions by inhibiting dietary fat absorption in the gastrointestinal tract, consequently decreasing caloric intake.

Administration Guidelines

For optimal efficacy, Ostat should be ingested orally with water during or within one hour following a fat-containing meal. Adherence to the prescribed dosing regimen is crucial. The standard protocol involves taking one capsule with each principal fat-containing meal, not exceeding three capsules daily.

Mechanism of Action

Orlistat, Ostat’s active pharmaceutical ingredient, is classified as a gastrointestinal lipase inhibitor. It exerts its therapeutic effect by covalently binding to pancreatic lipase enzymes, thereby preventing the hydrolysis of dietary triglycerides into absorbable free fatty acids and monoglycerides. This mechanism results in reduced fat absorption and consequent caloric deficit, facilitating weight management.

Therapeutic Advantages

Ostat provides multiple benefits for weight management, including:
• Significant reduction in dietary fat absorption (approximately 30%)
• Enhanced weight loss outcomes when combined with lifestyle modifications
• Potential improvement in obesity-related metabolic parameters
When incorporated into a comprehensive weight management program, Ostat can contribute to sustainable weight reduction and improved health metrics.

Adverse Effects

The most frequently reported adverse reactions involve the gastrointestinal system and are mechanism-related, including:
• Steatorrhea (oily/fatty stools)
• Increased defecation frequency
• Flatulence with discharge
• Abdominal discomfort
• Fecal urgency
These effects typically diminish with continued use and dietary fat restriction.

Dosage Protocol

The recommended posology is one 120mg capsule taken with each main meal containing dietary fat (maximum three capsules daily). Clinical efficacy is dependent on concomitant dietary modifications. Administration without fat-containing meals substantially reduces therapeutic effect.

Precautions and Contraindications

Ostat is contraindicated in:
• Pregnancy and lactation
• Hypersensitivity to orlistat or excipients
• Chronic malabsorption syndromes
• Cholestasis
Patients should disclose all concomitant medications, particularly antidiabetic agents and thyroid preparations, as drug interactions may occur. Regular monitoring of medication regimens is advised.

Storage Conditions

• Store at controlled room temperature (15-30°C)
• Protect from moisture and light
• Keep in original packaging
• Dispose of expired medication properly
• Maintain out of children’s reach

Note: This information serves educational purposes only and does not constitute medical advice. Consult your healthcare provider for personalized therapeutic recommendations.