Ciplar LA

✅ Controls high blood pressure
✅ Prevents heart attacks
✅ Reduces chest pain
✅ Manages irregular heartbeat
✅ Alleviates migraine symptoms

Ciplar LA contains Propranolol

Ciplar LA Tablet is prescribed to reduce anxiety and alleviate tremors. It also serves as a preventive treatment for migraines, angina (heart-related chest pain), and stomach bleeding caused by portal hypertension (high blood pressure in the liver).

This medication may additionally be used to manage hypertension and certain cardiac arrhythmias. The prescribed dosage varies based on your condition and individual response to treatment. Always follow your doctor’s instructions precisely. For optimal absorption, take this medication on an empty stomach at consistent times daily. Continue treatment even when feeling well, as the therapeutic benefits persist. Abrupt discontinuation may lead to worsening of symptoms.

Common adverse effects include fatigue, weakness, Raynaud’s phenomenon (cold extremities), bradycardia (slow heart rate), digital numbness, and dyspnea (shortness of breath). Gastrointestinal disturbances such as nausea, vomiting, and diarrhea may also occur. Consult your physician if side effects persist or become bothersome. Most reactions are transient and diminish with continued use as your body adapts to the medication.

Contraindications include asthma, severe bradycardia, and significant cardiac conditions like heart failure. Exercise caution and consult your doctor if you have renal or hepatic impairment or COPD. Alcohol consumption may interfere with drug efficacy and should be avoided. Refrain from driving if experiencing dizziness. Pregnant or breastfeeding individuals should seek medical advice before using this medication.

THERAPEUTIC INDICATIONS

  • Pheochromocytoma management
  • Essential hypertension
  • Migraine prophylaxis
  • Anxiety disorders
  • Cardiac arrhythmias
  • Myocardial infarction prevention
  • Angina pectoris prevention
  • Essential tremor management

CLINICAL BENEFITS

Pheochromocytoma Management

During surgical resection of pheochromocytoma, Ciplar LA Tablet mitigates the risk of hypertensive crisis by antagonizing catecholamine effects on the cardiovascular system. This pharmacological action reduces heart rate and myocardial contractility, effectively controlling blood pressure. The medication is particularly valuable for managing hypertensive emergencies. Maintaining optimal blood pressure significantly decreases the likelihood of cardiovascular events, cerebrovascular accidents, and renal complications.

ADVERSE EFFECTS

Most adverse reactions are transient and resolve spontaneously as therapy continues. Persistent symptoms warrant medical consultation.

Frequently Reported Reactions

  • Fatigue
  • Asthenia
  • Peripheral vasoconstriction
  • Cardiac conduction abnormalities
  • Gastrointestinal distress
  • Emesis
  • Loose stools

ADMINISTRATION GUIDELINES

Administer exactly as prescribed. Swallow the tablet whole without chewing, crushing, or breaking. Optimal absorption occurs when taken on an empty stomach.
Concurrent consumption with high-lipid foods (including olive oil, nuts, seeds, dark chocolate, dairy products, and meats) should be avoided.

PHARMACODYNAMICS

Ciplar LA Tablet contains propranolol hydrochloride, a non-selective beta-adrenergic antagonist. Its primary mechanism involves modulation of sympathetic nervous system activity, particularly myocardial response to catecholamines. The drug reduces sinoatrial node automaticity and atrioventricular conduction velocity, resulting in decreased heart rate and myocardial oxygen demand. Peripheral vasodilation improves coronary and systemic circulation, providing therapeutic benefits for angina and migraine prophylaxis. While the exact anti-tremor mechanism remains unclear, current evidence suggests central modulation of neuromuscular transmission. In anxiety management, propranolol competitively inhibits beta-adrenergic receptors, attenuating physiological manifestations of stress hormones. For pheochromocytoma, preoperative administration prevents catecholamine-induced hypertensive crises during tumor manipulation.

Medical Disclaimer:

This content is provided for informational purposes only after thorough review by medical professionals. While we strive for accuracy, this information should not replace professional medical advice, diagnosis, or treatment. The content does not encompass all potential adverse effects, drug interactions, or contraindications. Always consult your healthcare provider regarding any medical condition or treatment options. Our objective is to supplement, not substitute, the crucial relationship between patients and their physicians.
Strength

20 mg, 40 mg

Quantity

30 Tablet/s, 60 Tablet/s, 90 Tablet/s

Pharma Form

Tablet/s

Manufacturer

Cipla Inc

Treatment

Migraine, Chest pain (Angina), High blood pressure

Generic Brand

Treatment

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