Gel Cream

Product Overview

Crema Gel is a topical medication containing the active ingredient Diltiazem, formulated as a gel for external application. As a calcium channel blocker, it works by relaxing blood vessels to enhance circulation. This prescription gel is specifically indicated for treating anal fissures – painful tears in the anal lining – by reducing discomfort and promoting tissue healing.

Uses

This medicated gel is clinically proven to treat:
• Painful anal fissures (tears in anal mucosa)
• Chronic anal fissures resistant to conventional treatments
• Associated symptoms including bleeding, itching and sphincter spasms

How to Use

For optimal results:
1. Cleanse and dry affected area thoroughly
2. Apply pea-sized amount using clean fingertip
3. Gently massage into perianal skin (avoiding direct wound contact)
4. Wash hands immediately post-application
5. Repeat 2-3 times daily or as prescribed

Mechanism of Action

Diltiazem exerts its therapeutic effects by:
• Blocking calcium channels in smooth muscle
• Reducing anal sphincter hypertonicity
• Increasing local blood circulation
• Promoting tissue repair mechanisms

Dosage Guidelines

Standard therapeutic protocol:
• Apply 0.5-1 cm gel strip 2-3 times daily
• Treatment duration: Typically 6-8 weeks
• Maximum daily dose: 3 applications
Note: Always follow your physician’s specific instructions

Therapeutic Benefits

Clinical advantages include:
• Significant pain reduction (80% patients report relief within 1 week)
• 70% faster healing vs. conservative treatments
• Non-invasive alternative to surgical options
• Minimal systemic absorption

Potential Side Effects

Reported adverse reactions (incidence <5%): • Localized erythema • Transient burning sensation • Mild perianal irritation • Contact dermatitis (rare)

Important Precautions

Contraindications and warnings:
• Hypersensitivity to diltiazem hydrochloride
• Avoid ocular/mucosal contact
• Not recommended for:
– Open wounds
– Active infections
– Hemorrhagic conditions
• Pregnancy Category C: Use only if potential benefit justifies risk

Storage Conditions

Proper storage requirements:
• Temperature: 15-30°C
• Protect from light and moisture
• Keep tube tightly sealed
• Do not refrigerate or freeze
• Shelf life: 24 months from manufacture

Medical Disclaimer

This information is provided for educational purposes only and does not constitute medical advice. While we strive for accuracy, this content is not exhaustive and may not reflect the most current medical developments. Always:
• Consult your healthcare provider
• Review the official package insert
• Report any adverse reactions
• Never disregard professional medical advice