Diabetrol SR

Product Overview

Diabetrol SR is a pharmaceutical formulation containing the active components Glibenclamide and Metformin Hydrochloride.

Therapeutic Applications

This medication is specifically indicated for the treatment and management of Type 2 diabetes mellitus, assisting in the regulation of blood glucose levels in diagnosed patients.

Mechanism of Action

The dual active ingredients operate through complementary mechanisms:

• Glibenclamide (a sulfonylurea derivative) stimulates insulin secretion from pancreatic β-cells
• Metformin Hydrochloride reduces hepatic glucose production while enhancing peripheral insulin sensitivity

This synergistic action facilitates improved glycemic control.

Dosage Guidelines

Administration should strictly follow medical prescription, with dosage adjustments based on:

• Individual metabolic response
• Patient age
• Clinical condition

The sustained-release formulation allows for oral administration with or without meals. If a dose is missed, take it when remembered unless approaching the next scheduled dose. Never exceed prescribed amounts.

Therapeutic Advantages

Diabetrol SR provides comprehensive glycemic management through its dual-component formulation, offering:

• Enhanced blood sugar regulation
• Reduced risk of diabetes-related complications (nephropathy, neuropathy, retinopathy)
• Improved long-term metabolic outcomes

Potential Adverse Effects

While generally well-tolerated, some patients may experience:

• Gastrointestinal disturbances (nausea, diarrhea)
• Hypoglycemic episodes
• Dermatological reactions
• Moderate weight fluctuations

These effects are typically transient and dose-dependent.

Important Precautions

• Contraindicated in Type 1 diabetes and diabetic ketoacidosis
• Alcohol consumption may potentiate hypoglycemic effects
• Requires medical supervision in pregnancy/lactation
• Discontinue immediately and seek emergency care for severe hypersensitivity reactions

Storage Conditions

Maintain product integrity by storing:

• At controlled room temperature (15-30°C)
• Protected from moisture and light
• In child-resistant packaging

Medical Disclaimer:
The information provided herein represents carefully reviewed pharmaceutical data intended for educational purposes only. This content does not constitute medical advice nor replace professional clinical judgment. Healthcare providers should be consulted for:

• Personalized treatment plans
• Comprehensive safety information
• Management of potential drug interactions

This resource aims to supplement, not substitute, the essential physician-patient relationship.