Iotim Eye Drops

Product Overview

Iotim Eye Drops contain the active ingredient Timolol (0.5% w/v) formulated as ophthalmic drops. As a beta-adrenergic blocking agent, Timolol reduces aqueous humor production in the eye. This mechanism effectively lowers intraocular pressure, making Iotim Eye Drops an essential treatment for glaucoma and ocular hypertension.

Therapeutic Indications

Iotim Eye Drops are indicated for:
– Chronic open-angle glaucoma
– Angle-closure glaucoma (as adjunct therapy)
– Ocular hypertension

By controlling elevated intraocular pressure, this medication helps prevent progressive optic nerve damage and subsequent vision impairment associated with these conditions.

Administration Instructions

For proper administration:
1. Wash hands thoroughly before use
2. Tilt head back and gently pull lower eyelid downward
3. Instill prescribed number of drops into conjunctival sac
4. Close eyes gently for 1-2 minutes
5. Apply gentle pressure to lacrimal sac (for 1 minute) to minimize systemic absorption
6. Avoid contact between dropper tip and ocular surface

Mechanism of Action

Timolol maleate, a nonselective beta-adrenergic receptor antagonist, exerts its therapeutic effect by:
– Inhibiting cAMP-dependent aqueous humor production in ciliary epithelium
– Reducing intraocular pressure by 20-30%
– Maintaining consistent pressure reduction with twice-daily dosing

Dosage Regimen

Standard dosage:
– Initial: 1 drop of 0.5% solution in affected eye(s) twice daily
– Maintenance: May be adjusted to once daily based on therapeutic response

Important considerations:
– Wait ≥5 minutes between administering multiple ophthalmic medications
– Contact lens wearers should remove lenses prior to administration
– Reinsertion may occur 15 minutes post-instillation

Therapeutic Benefits

• Significant intraocular pressure reduction (25-30%)
• Proven efficacy in various glaucoma subtypes
• Neuroprotective effect on retinal ganglion cells
• Convenient dosing schedule
• Established safety profile

Adverse Reactions

Common ocular effects:
– Transient burning/stinging (15-30% patients)
– Superficial punctate keratitis
– Dry eye symptoms
– Allergic conjunctivitis

Systemic effects (rare):
– Bradycardia
– Bronchospasm
– Hypotension

Precautions

Contraindications:
– Bronchial asthma
– Severe COPD
– Sinus bradycardia
– 2nd/3rd degree AV block

Special warnings:
– May mask hypoglycemia symptoms in diabetics
– Caution in patients with myasthenia gravis
– Potential additive effects with systemic beta-blockers
– Temporary blurred vision may affect driving ability

Storage Conditions

Optimal storage:
– Temperature: 15-25°C
– Protect from light and moisture
– Keep container tightly closed
– Discard 28 days after opening
– Do not use beyond expiration date

Medical Disclaimer

This information is provided for educational purposes only and does not constitute medical advice. While we strive for accuracy, this content may not encompass all potential drug interactions, contraindications, or adverse effects. Always consult your healthcare provider for personalized medical guidance. This information supplements but does not replace professional medical judgment or the physician-patient relationship.