Lametec-100 DT

Product Overview

Lametec-100 DT is a pharmaceutical formulation containing Lamotrigine as its active component. This prescription anticonvulsant medication is primarily indicated for the management of epilepsy and bipolar disorder. The drug functions by stabilizing neuronal electrical activity and suppressing abnormal nerve cell firing, thereby decreasing seizure frequency in epilepsy and regulating mood fluctuations in bipolar disorder. The orally disintegrating tablet (DT) formulation allows rapid dissolution in the oral cavity without requiring water, offering enhanced convenience particularly for patients with swallowing difficulties.

Therapeutic Applications

This medication is prescribed for:
– Management of epileptic seizures (partial, tonic-clonic, and generalized seizures)
– Maintenance therapy for bipolar disorder to prevent recurrence of mood episodes (depressive, manic, hypomanic, or mixed states)

Administration Guidelines

For proper use:
1. Place the orally disintegrating tablet on the tongue
2. Allow complete dissolution (typically within seconds)
3. Swallow the dissolved medication without chewing
4. May be taken with or without food as directed
5. Tablets may be divided if swallowing difficulty persists
6. Strictly adhere to prescribed dosage and frequency

Mechanism of Action

Lamotrigine, the active pharmaceutical ingredient, exerts its therapeutic effects through:
– Modulation of voltage-gated sodium channels
– Regulation of glutamate receptor activity
– Stabilization of neuronal membranes
– Normalization of neurotransmitter activity
These pharmacological actions collectively reduce abnormal electrical discharges in epilepsy and stabilize mood regulation in bipolar disorder.

Dosage Protocol

Dosing considerations:
– Individualized based on patient characteristics and therapeutic response
– Epilepsy: Initial dose typically 25 mg daily for 2 weeks, followed by gradual titration
– Bipolar disorder: Starting dose usually 25 mg daily with subsequent adjustments
– Strict adherence to prescribed regimen essential for optimal outcomes

Therapeutic Advantages

Key clinical benefits include:
– Effective seizure control in epilepsy
– Mood stabilization in bipolar disorder
– Reduced frequency of mood episodes
– Improved quality of life and functional capacity
– Convenient administration format

Adverse Effects

Commonly reported reactions:
– Neurological: Dizziness, headache, drowsiness
– Visual disturbances
– Gastrointestinal complaints (nausea, vomiting)
– Sleep pattern alterations
– Dermatological reactions (typically mild rashes)
Most side effects are transient and diminish with continued therapy.

Important Precautions

Critical safety considerations:
– Potential for serious dermatological reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis)
– Requires immediate medical attention for any skin manifestations
– Regular hepatic function monitoring recommended
– Caution required in patients with renal impairment
– Gradual dose titration minimizes adverse effects

Storage Requirements

Proper storage conditions:
– Maintain at controlled room temperature
– Protect from moisture and heat exposure
– Store in original packaging
– Keep away from children and pets
– Avoid bathroom or kitchen storage due to humidity

Disclaimer:

The information provided is intended for educational purposes only and represents expert-reviewed, accurate content. This material should not substitute professional medical advice, diagnosis, or treatment. Please consult your healthcare provider for:
– Complete information about potential side effects
– Drug interaction possibilities
– Disease-specific guidance
– Personalized treatment recommendations
This content aims to support, not replace, the crucial relationship between patients and their healthcare providers.