Tenvir AF

Product Overview

Tenvir AF is an antiviral medication formulated with Tenofovir Alafenamide (25mg) as its active ingredient. Presented in tablet form, it falls under the category of nucleotide reverse transcriptase inhibitors (NRTIs). This medication is primarily prescribed for managing human immunodeficiency virus (HIV) infections and chronic hepatitis B virus (HBV) infections. Tenvir AF exerts its therapeutic effect by inhibiting the reverse transcriptase enzyme, a crucial component for viral replication in both HIV and HBV. This inhibition helps control viral proliferation and reduces the viral burden in patients.

Uses

Tenvir AF is approved for:
– Treatment of HIV-1 infection in adults and pediatric patients (≥25 kg body weight)
– Management of chronic HBV infection in adults and pediatric patients (≥35 kg body weight)
The medication aids in slowing disease progression, decreasing the likelihood of developing AIDS or liver-related complications, and enhancing overall health outcomes for affected individuals.

How to Use

Administration Guidelines:
– Take one tablet orally once daily
– May be taken with or without food
– Swallow whole with water (do not chew, crush, or break)
– Maintain consistent dosing schedule for optimal efficacy
– Do not discontinue without medical supervision to prevent treatment failure and resistance development

How it Works

Tenvir AF contains Tenofovir Alafenamide, a prodrug that metabolizes into active tenofovir within the body. The active compound specifically targets and inhibits reverse transcriptase, the enzyme responsible for converting viral RNA into DNA. By disrupting this critical step in viral replication, Tenvir AF effectively suppresses viral multiplication and reduces viral load.

Dosage and Administration

Standard Dosage:
– HIV-1 treatment: 1 tablet daily (patients ≥25 kg)
– Chronic HBV treatment: 1 tablet daily (patients ≥35 kg)
Dosage may require adjustment based on individual patient factors and therapeutic response. Always adhere to prescribing physician’s instructions.

Benefits

• Effective dual-action against HIV-1 and chronic HBV infections
• Suppresses viral replication and lowers viral load
• Enhances immune function and slows disease progression
• Convenient once-daily dosing improves treatment adherence
• Generally well-tolerated with favorable safety profile

Common Side Effects

Frequently reported adverse effects include:
– Gastrointestinal disturbances (nausea, vomiting, diarrhea)
– Headache
– Fatigue
– Abdominal discomfort
These symptoms are typically mild to moderate and often diminish with continued therapy. Persistent or severe reactions should be reported to a healthcare professional.

Warnings

Important Safety Considerations:
– Potential for renal impairment (monitor kidney function)
– Possible bone mineral density reduction
– Risk of hepatic complications
– May interact with other medications (disclose all concurrent drugs)
Seek immediate medical attention for symptoms of kidney/liver dysfunction (e.g., oliguria, edema, jaundice, dark urine).

Storage Information

Storage Requirements:
– Maintain at room temperature (15-30°C)
– Protect from moisture and heat
– Keep in original packaging
– Store out of children’s and pets’ reach
Do not use if packaging integrity is compromised.

Disclaimer:

This information is provided for educational purposes only and represents expert-reviewed, accurate content. It is not intended as medical advice nor as a substitute for professional healthcare consultation. The content may not encompass all potential side effects, drug interactions, or contraindications. Always consult with a qualified physician regarding any medical condition or treatment. Our aim is to supplement, not replace, the crucial relationship between patients and their healthcare providers.