Walapan-40

Product Overview

Walapan-40 is a proton pump inhibitor (PPI) medication containing Pantoprazole as its active ingredient. Available as delayed-release tablets, it’s clinically proven to effectively manage excessive stomach acid production. This prescription medication treats gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome by significantly reducing gastric acid secretion. The 40 mg tablets provide relief from acid-related symptoms including persistent heartburn, acid regurgitation, and dyspepsia when taken orally once daily before breakfast.

Therapeutic Applications

Pantoprazole-based Walapan-40 is indicated for:
• Short-term GERD management (4-8 weeks)
• Healing and maintenance therapy for erosive esophagitis
• Treatment of gastric and duodenal ulcers
• NSAID-induced ulcer prophylaxis
• Management of pathological hypersecretory conditions like Zollinger-Ellison syndrome

Administration Guidelines

For optimal results:
1. Take one 40 mg tablet daily before morning meal
2. Swallow whole with 240ml water
3. Avoid crushing/chewing tablets
4. Maintain consistent dosing schedule
5. Maximum daily dose: 40mg unless medically advised

Mechanism of Action

Pantoprazole exerts its therapeutic effect through irreversible inhibition of gastric parietal cell H+/K+ ATPase pumps. This molecular action:
• Suppresses basal and stimulated acid secretion
• Creates prolonged antisecretory effect (>24 hours)
• Elevates gastric pH to therapeutic levels
• Promotes mucosal healing in acid-damaged tissues

Dosage Protocol

Standard adult dosage:
• Single 40mg tablet daily (morning)
• GERD treatment duration: 4-8 weeks
• Maintenance therapy: lowest effective dose
• Renal/hepatic impairment: no adjustment typically needed

Therapeutic Advantages

Clinical benefits include:
• Rapid and sustained acid suppression
• Significant symptom relief within 2-3 days
• High healing rates for erosive esophagitis
• Reduced ulcer recurrence rates
• Improved quality of life for chronic sufferers

Adverse Effects

Common (1-10% incidence):
• Gastrointestinal: nausea (4%), diarrhea (3%), abdominal pain (2%)
• Neurological: headache (5%), dizziness (2%)
• General: flatulence (2%)

Serious (require medical attention):
• Severe cutaneous reactions
• Hypomagnesemia (prolonged use)
• Vitamin B12 deficiency (long-term therapy)
• Clostridium difficile-associated diarrhea

Important Precautions

Medical consultation required if:
• History of liver cirrhosis
• Concurrent warfarin therapy
• Osteoporosis risk factors present
• Pregnancy/lactation consideration
• Planned long-term (>1 year) therapy

Storage Conditions

• Store below 30°C in original packaging
• Protect from moisture and light
• Keep out of children’s reach
• Discard expired tablets properly
• Do not use damaged/discolored tablets

Medical Disclaimer

This information serves educational purposes only and does not constitute medical advice. While we strive for accuracy, individual responses to medication may vary. Always:
• Consult your healthcare provider before use
• Disclose complete medical history
• Report any unusual symptoms
• Review full prescribing information
• Maintain regular medical follow-ups

The doctor-patient relationship remains paramount in all treatment decisions.