Propranolol SR

✅ Enhances Heart Health
✅ Controls Blood Pressure
✅ Reduces Anxiety Levels
✅ Improves Sleep Quality
✅ Minimizes Panic Attacks

Provanol SR contains Propranolol

Provanol SR 80 Tablet is prescribed to reduce anxiety and alleviate tremors. It’s also effective in preventing migraines, angina (heart-related chest pain), and stomach bleeding caused by portal hypertension (high blood pressure in the liver).

This medication may additionally be used to manage hypertension and certain cardiac arrhythmias. The prescribed dosage varies based on your condition and individual response to treatment. Always follow your doctor’s instructions precisely. For optimal absorption, take this medication on an empty stomach at consistent times daily. Continue treatment even when feeling well, as the therapeutic benefits persist. Abrupt discontinuation may cause your condition to deteriorate.

Common adverse effects include fatigue, weakness, cold extremities (Raynaud’s phenomenon), bradycardia or irregular heartbeat, finger numbness, and dyspnea. Gastrointestinal disturbances like nausea, vomiting, and diarrhea may also occur. Consult your physician if side effects persist or become bothersome. Most reactions are transient and diminish as your system adapts to the medication.

Contraindications include asthma, severe bradycardia, significant cardiac conduction disorders, and heart failure. Exercise caution with renal/hepatic impairment or COPD. Alcohol consumption may interfere with drug efficacy and should be avoided. Refrain from driving if experiencing dizziness. Pregnant or breastfeeding women should seek medical advice before use.

THERAPEUTIC INDICATIONS

  • Pheochromocytoma management
  • Essential hypertension
  • Migraine prophylaxis
  • Anxiety disorders
  • Cardiac arrhythmias
  • Myocardial infarction prevention
  • Angina pectoris prophylaxis
  • Essential tremor

CLINICAL BENEFITS

Pheochromocytoma Management

During surgical resection of pheochromocytoma, Provanol SR 80 Tablet mitigates catecholamine-induced hypertensive crises by competitively blocking β-adrenergic receptors. This pharmacological action reduces myocardial contractility and heart rate, effectively controlling blood pressure. Timely blood pressure normalization decreases cardiovascular complications including myocardial infarction, cerebrovascular accidents, and renal impairment.

ADVERSE EFFECTS

Most adverse reactions are self-limiting and resolve with continued therapy as physiological adaptation occurs. Persistent symptoms warrant medical consultation.

Frequently Reported Reactions

  • Fatigue
  • Asthenia
  • Peripheral vasospasm
  • Cardiac conduction abnormalities
  • Gastrointestinal distress
  • Emesis
  • Loose stools

ADMINISTRATION GUIDELINES

Administer exactly as prescribed. Swallow the sustained-release tablet whole without chewing or crushing. Optimal absorption occurs when taken preprandially.
Concurrent consumption with high-lipid foods (including olive oil, tree nuts, cocoa products, dairy fats, and animal proteins) may impair drug absorption.

PHARMACODYNAMICS

Provanol SR 80 Tablet contains propranolol hydrochloride, a non-selective β-adrenergic antagonist. Its therapeutic effects stem from competitive inhibition of catecholamine binding at β1- and β2-adrenergic receptors. This results in negative chronotropic and inotropic cardiac effects, reducing myocardial oxygen demand and preventing arrhythmias. Peripheral vasodilation improves coronary and cerebral perfusion, preventing anginal episodes and migraines. While the precise anti-tremor mechanism remains unclear, proposed theories include peripheral β2-receptor blockade in skeletal muscle and central modulation of noradrenergic pathways. In anxiety management, it attenuates somatic symptoms by blocking peripheral adrenergic stimulation. For pheochromocytoma, preoperative β-blockade prevents catecholamine-induced hypertensive emergencies during tumor manipulation.

Medical Disclaimer:

This content is provided for informational purposes only after rigorous medical review. It is not intended to replace professional medical advice, diagnosis, or treatment. The information presented may not encompass all potential adverse effects, contraindications, or drug interactions. Always consult your healthcare provider regarding any medical condition or therapeutic regimen. Our objective is to supplement, not supplant, the crucial physician-patient relationship.
Strength

80 mg

Quantity

30 Tablet/s, 60 Tablet/s, 90 Tablet/s

Pharma Form

Tablet/s

Manufacturer

Intas Pharma

Treatment

Migraine, Chest pain (Angina), High blood pressure

Generic Brand

Propranolol

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