Ranitidine 300

Product Overview

Rantac is a pharmaceutical formulation containing Ranitidine (300mg) as its active component. This tablet medication is classified as an H2 receptor antagonist, effectively decreasing gastric acid secretion. Clinically prescribed for managing gastrointestinal disorders, Rantac alleviates symptoms including pyrosis, acid dyspepsia, and gastroesophageal reflux disease (GERD), thereby enhancing digestive system functionality.

Therapeutic Indications

This pharmacotherapeutic agent is indicated for:

• Symptomatic management of hyperchlorhydria-related conditions
• Therapeutic intervention for peptic ulcer disease (gastric and duodenal)
• Prophylactic management of ulcer recurrence

The mechanism involves competitive inhibition of histamine H2-receptors on gastric parietal cells, resulting in diminished basal and stimulated acid secretion.

Administration Protocol

For optimal therapeutic outcomes:

1. Administer orally with 240mL water
2. Recommended timing: 30 minutes preprandial or at bedtime
3. Swallow tablets intact – do not crush or chew
4. Maintain consistent dosing schedule

Pharmacodynamics

Ranitidine exhibits:

• Dose-dependent suppression of gastric acid secretion
• 75-80% reduction in basal acid output
• Significant decrease in pepsin concentration
• Duration of action: 8-12 hours

Posology

Standard dosing regimen:

Therapeutic Advantages

Clinical benefits include:

• Rapid symptomatic relief (onset within 1 hour)
• Enhanced mucosal healing rates
• Reduced nocturnal acid breakthrough
• Favorable safety profile

Adverse Effects

Common adverse drug reactions (≥1% incidence):

• Cephalalgia (11.7%)
• Gastrointestinal disturbances (4.8%)
• Vertigo (2.4%)

Precautions

Special populations requiring monitoring:

• Renal impairment (CrCl <50mL/min)
• Hepatic dysfunction (Child-Pugh B/C)
• Elderly patients (>65 years)

Storage Conditions

Maintain product integrity by:

• Storing at 15-30°C
• Protecting from humidity
• Keeping in original packaging

Medical Disclaimer

This information serves educational purposes only and does not constitute medical advice. Healthcare providers should be consulted for:

• Individualized treatment plans
• Comprehensive risk-benefit analysis
• Management of potential drug interactions

The content aims to supplement, not replace, professional medical judgment. Always verify expiration dates prior to administration.