Feline Revolution

Product Overview

Revolution is a veterinary parasiticide formulated to prevent and eradicate flea and mite infestations in small animals, including rabbits and cats (from 8 weeks of age). This single-dose topical solution contains Selamectin as its active ingredient and provides comprehensive protection against ear mites, sarcoptic mange, and cheyletiellosis. The fast-drying, non-greasy formula becomes waterproof within two hours of application, permitting immediate pet interaction without residual odor.

Indications

Revolution is clinically proven for:

• Prevention and treatment of flea infestations
• Eradication of ear mites (Otodectes cynotis)
• Management of sarcoptic mange (Sarcoptes scabiei)
• Control of cheyletiellosis (walking dandruff)

The formulation provides ovicidal activity against flea eggs while eliminating adult fleas, breaking the parasite life cycle and preventing reinfestation.

Administration Guidelines

1. Calculate dosage at 0.1cc per kg body weight
2. Apply directly to dry skin at the base of the skull
3. Ensure application site remains undisturbed during absorption
4. Implement environmental decontamination protocols post-application

The formulation achieves optimal transdermal absorption within two hours, after which water exposure does not diminish efficacy.

Mechanism of Action

Selamectin, a macrocyclic lactone, exerts its parasiticidal effect through:

• GABA receptor agonism in arthropod nervous systems
• Glutamate-gated chloride channel modulation
• Resultant neuromuscular paralysis and parasite death

This dual mechanism provides both adulticidal and ovicidal activity against target parasites.

Dosage Protocol

Administration requires precise measurement using a needle-free syringe. Apply to non-groomable areas only.

Therapeutic Advantages

• Broad-spectrum ectoparasiticide with residual activity
• Rapid dermal absorption (2-hour waterproofing)
• Non-irritating, alcohol-free formulation
• Monthly application protocol
• Pediatric safety (≥8 weeks)

Adverse Effects

Potential transient reactions may include:

• Localized alopecia (2.3% incidence)
• Erythema at application site (1.1%)
• Pruritus (0.7%)

Hypersensitivity reactions (angioedema, dyspnea) require immediate veterinary intervention.

Precautionary Measures

• Contraindicated in ivermectin-sensitive breeds
• Exercise caution in gravid/lactating animals
• Wear gloves during application
• Maintain 24-hour observation post-application
• Store at controlled room temperature (15-30°C)

Storage Requirements

• Protect from light and excessive heat
• Maintain original packaging integrity
• Discard expired product per hazardous waste regulations

Medical Disclaimer

This information represents current pharmacological data but does not constitute veterinary advice. While we strive for accuracy, the complexity of individual cases necessitates professional consultation. This content supplements but does not replace the veterinarian-client-patient relationship. Always verify treatment protocols with licensed practitioners, particularly for patients with comorbidities or concurrent medication regimens. Report adverse events to appropriate regulatory authorities.