Riochi 1

Product Overview

Rioci is a prescription medication containing the active ingredient Riociguat, formulated as oral tablets. As a vasodilator, Riociguat works by relaxing blood vessels and enhancing oxygen-rich blood flow to the lungs. This medication is specifically indicated for treating two forms of pulmonary hypertension: pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH), both characterized by abnormally high blood pressure in the lung arteries.

Uses

Rioci tablets are prescribed to:
– Improve exercise capacity
– Slow disease progression
in patients with:
1. Pulmonary arterial hypertension (PAH) – a progressive condition causing dangerously high blood pressure in lung arteries, leading to breathlessness, fatigue, and reduced physical endurance
2. Chronic thromboembolic pulmonary hypertension (CTEPH) – a rare form caused by lung blood clots

Administration Instructions

Take Rioci tablets orally with or without food as directed by your physician. Swallow tablets whole with water – do not crush, chew, or split them. Maintain consistent dosing as prescribed for optimal results. If you miss a dose, take it when remembered, but never double dose to compensate.

Mechanism of Action

Riociguat, the active component in Rioci, is a soluble guanylate cyclase stimulator. It enhances production of cyclic guanosine monophosphate (cGMP), a signaling molecule that promotes blood vessel relaxation and dilation. By widening pulmonary arteries, Rioci reduces lung vascular resistance, lowers blood pressure, and improves physical capacity in pulmonary hypertension patients.

Dosage Guidelines

For PAH:
– Initial dose: 1 mg three times daily
– May titrate up to maximum: 2.5 mg three times daily
(based on individual response and tolerance)

For CTEPH:
– Initial dose: 0.5 mg three times daily
– Maximum dose: 2.5 mg three times daily

Storage: Keep at room temperature, protected from moisture and heat.

Therapeutic Benefits

Rioci provides multiple clinical benefits:

• Enhanced physical endurance and functional ability
• Reduced pulmonary vascular resistance
• Slowed disease advancement and improved survival
• Symptom relief (reduced breathlessness and fatigue)

Common Adverse Effects

Frequently reported side effects include:
– Headache
– Dizziness
– Nausea
– Diarrhea
– Hypotension
These are typically mild-to-moderate and may subside with continued use. Consult your healthcare provider if symptoms persist or intensify.

Important Precautions

Exercise caution with Rioci if you have:
– Low blood pressure
– Liver/kidney dysfunction
– Bleeding disorders
– Cardiovascular history

Contraindications:
– Pregnancy (risk of fetal harm)

Drug Interactions:
May potentiate hypotensive effects when combined with:
– Nitrates
– Antihypertensives
– Phosphodiesterase inhibitors

Always disclose all medications, supplements, and medical conditions to your doctor before starting Rioci.

Proper Storage

– Store at room temperature (15-30°C)
– Protect from moisture and heat
– Keep out of children’s and pets’ reach
– Do not use expired medication

Disclaimer:

This information is provided for educational purposes only and represents expert-reviewed, accurate content. However, it does not replace professional medical advice, diagnosis, or treatment. The content may not include all possible side effects, interactions, or warnings. Always consult your physician regarding any health condition or medication. Our goal is to supplement, not replace, the crucial doctor-patient relationship.