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Product Overview

Taficita is an antiretroviral medication combining Emtricitabine (200mg) and Tenofovir disoproxil fumarate (25mg) in tablet form. This fixed-dose combination therapy is prescribed for managing HIV-1 infection in adults and pediatric patients weighing ≥17kg. As part of the nucleoside reverse transcriptase inhibitor (NRTI) class, Taficita works by blocking HIV viral replication, effectively lowering viral load in patients.

Therapeutic Indications

Taficita is approved for HIV-1 treatment in:

• Adults
• Pediatric patients (≥17kg body weight)

This medication must be used in combination with other antiretroviral drugs as part of complete HIV treatment regimen. By inhibiting viral reproduction, Taficita helps:

• Slow HIV disease progression
• Maintain immune function
• Reduce opportunistic infection risks

Administration Guidelines

Dosage: One tablet daily (with/without food)
Instructions:

• Swallow tablet whole with water
• Do not crush, chew, or split
• Maintain consistent dosing schedule

Special Populations: Renal impairment may require dosage adjustment

Mechanism of Action

Taficita‘s dual active components target HIV replication through:

1. Emtricitabine: Cytosine analogue inhibiting reverse transcriptase
2. Tenofovir DF: Adenosine nucleotide analogue blocking viral DNA chain elongation

This synergistic action prevents viral RNA→DNA conversion, effectively suppressing new virus formation.

Dosage Specifications

Patient Group	Dosage
Adults & Pediatrics (≥17kg)	1 tablet daily
Renal Impairment	Dosage adjustment required

Therapeutic Advantages

• Dual-action viral suppression
• Simplified once-daily regimen
• Established safety profile
• Effective across age groups
• Supports long-term viral control

Adverse Effects

Common (≥5%):

• Gastrointestinal: Nausea, diarrhea, abdominal discomfort
• General: Headache, fatigue

Management: Typically transient; consult physician if persistent

Important Considerations

• Monitor renal function regularly
• Disclose all concomitant medications
• Report any unusual symptoms
• Maintain strict adherence

Safety Precautions

Contraindications:

• Severe hepatic impairment
• Hypersensitivity to components

Warnings:

• Renal monitoring required
• Potential bone mineral density effects
• Lactic acidosis risk (rare)

Storage Requirements

• Store at 15-30°C
• Protect from moisture
• Keep in original packaging
• Store away from children

Medical Disclaimer

This information serves educational purposes only and does not replace professional medical advice. Consult your healthcare provider for:

• Personalized treatment plans
• Adverse effect management
• Drug interaction assessments

Always follow your physician’s guidance regarding HIV treatment and medication use.