Teravir

Product Overview

Teravir is an antiviral medication formulated with Tenofovir disoproxil fumarate (300mg) as its active ingredient. Presented in tablet form, this pharmaceutical belongs to the nucleoside reverse transcriptase inhibitor (NRTI) class and is indicated for the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. By inhibiting viral replication, Teravir helps control disease progression and supports immune system function.

Therapeutic Applications

This medication is approved for:
– HIV-1 infection management in adults and pediatric patients (≥17 kg/37.5 lbs)
– Chronic HBV infection treatment in adults

For HIV patients, Teravir is administered as part of combination antiretroviral therapy. In HBV cases, it effectively suppresses viral activity, mitigates hepatic inflammation, and reduces the likelihood of liver complications.

Administration Guidelines

Take Teravir orally once daily, with or without food, as prescribed. Swallow tablets whole with water – do not crush, chew, or split. Consistent daily dosing at the same time maintains therapeutic drug levels. Adherence to the prescribed regimen is crucial to prevent reduced efficacy and potential viral resistance.

Mechanism of Action

Following ingestion, Tenofovir disoproxil fumarate undergoes metabolic conversion to tenofovir diphosphate, the active moiety. This compound selectively inhibits HIV/HBV reverse transcriptase, an enzyme essential for viral replication. By disrupting this process, Teravir effectively reduces viral load, slows disease advancement, and helps preserve immune competence.

Dosage Protocol

Standard dosing:
– HIV treatment: 300mg once daily (adults and pediatric patients ≥17kg)
– Chronic HBV: 300mg once daily (adults)

Renal impairment necessitates dosage adjustment. Strict adherence to healthcare provider instructions is essential for optimal therapeutic outcomes.

Therapeutic Advantages

• Dual indication for HIV and chronic HBV management
• Effective viral suppression and load reduction
• Immunoprotective effects
• Simplified once-daily dosing schedule
• Generally favorable tolerability profile

Adverse Effects

Common reactions may include:
– Gastrointestinal disturbances (nausea, vomiting, diarrhea)
– Neurological symptoms (headache, dizziness)
– General malaise (fatigue)

These typically present as mild-to-moderate and often diminish with continued therapy. Persistent or troublesome effects warrant medical consultation.

Important Safety Considerations

Renal monitoring is imperative as Teravir may:
– Impair kidney function
– Potentially cause renal failure (particularly in predisposed patients)

Additionally, the medication carries risk of lactic acidosis – a potentially fatal metabolic condition. Immediate medical attention is required for symptoms including:
– Tachypnea
– Gastrointestinal distress
– Unexplained weakness
– Abdominal discomfort

Storage Requirements

Maintain at controlled room temperature (15-30°C) in original packaging. Protect from moisture and excessive heat. Keep securely stored away from children and pets. Discard if packaging integrity is compromised.

Medical Disclaimer

This information serves educational purposes only and does not constitute medical advice. While we strive to provide accurate, expert-reviewed content, it should not replace professional medical consultation. Not all potential interactions, contraindications, or adverse effects are listed herein. Always consult your healthcare provider regarding treatment options and health concerns. Our aim is to complement, not substitute, the essential physician-patient relationship.