Urifon

Product Overview

Urifon is an antibiotic medication containing Nitrofurantoin as its active ingredient. Specifically formulated to combat urinary tract infections (UTIs), this oral capsule treatment effectively targets susceptible bacterial strains. By disrupting bacterial DNA, RNA, and protein synthesis, Urifon halts microbial growth and proliferation, offering a reliable solution for UTI sufferers.

Uses

This medication is indicated for:
– Treating acute uncomplicated UTIs (including cystitis and urethritis)
– Preventing recurrent urinary tract infections
– Addressing symptoms like dysuria, urinary frequency, urgency, and pelvic discomfort
Urifon demonstrates particular effectiveness against Escherichia coli and other common uropathogens.

How to Use

Administration guidelines:
• Take capsules whole with 240ml (8oz) of water
• May be consumed with meals or dairy products to reduce GI irritation
• Maintain consistent dosing intervals
• Complete entire prescribed course (typically 5-7 days)
• Do not discontinue early, even with symptom resolution

How it Works

As a nitrofuran derivative, Urifon exerts its bactericidal effects through:
1. Inhibition of bacterial acetyl-CoA metabolism
2. Disruption of ribosomal protein synthesis
3. Interference with DNA/RNA formation
This multi-target mechanism minimizes resistance development while effectively eradicating urinary pathogens.

Dosage and Administration

Standard dosing regimens:
• Acute treatment: 50-100mg QID for 7 days
• Prophylaxis: 50-100mg nocte
Special populations:
• Renal impairment: Adjust per CrCl
• Elderly: Monitor for adverse effects
• Pediatrics: Not recommended <12 years

Benefits

Therapeutic advantages include:
✓ High urinary concentration (95% renal excretion)
✓ Low systemic absorption
✓ Targeted action against common uropathogens
✓ Reduced recurrence rates in chronic UTIs
✓ Minimal impact on gut microbiota

Common Side Effects

Frequently reported reactions (≥1%):
• Gastrointestinal: Nausea (10%), diarrhea (4%)
• Neurological: Headache (3%), dizziness (2%)
• Respiratory: Mild pulmonary reactions (rare)
These typically resolve with continued therapy or dose adjustment.

Warnings

Important precautions:
■ Contraindicated in:
– CrCl <60mL/min - Pregnancy (third trimester) - G6PD deficiency ■ Requires monitoring in: - Hepatic impairment - Chronic pulmonary conditions ■ Potential interactions with: - Magnesium-containing antacids - Probenecid - Uricosuric agents

Storage Information

Optimal storage conditions:
• Temperature: 20-25°C (68-77°F)
• Protection from:
– Moisture
– Direct sunlight
– Extreme temperatures
• Keep in original packaging
• Discard expired medication properly

Disclaimer:

This information serves educational purposes only and does not constitute medical advice. While we strive for accuracy, healthcare decisions should always be made in consultation with qualified medical professionals. The content may not encompass all potential adverse effects, contraindications, or drug interactions. Patients are advised to:
• Disclose complete medical history
• Report any unusual symptoms
• Follow prescribed treatment plans
• Maintain regular physician contact