Anti-Nausea

Product Description

Vomistop tablet is a domperidone-based medication designed to effectively manage indigestion, nausea, and vomiting. This formulation enhances gastrointestinal motility, facilitating faster movement of food through the digestive tract while providing relief from bloating, abdominal fullness, and gastric discomfort.

Uses

This medication is clinically indicated for:
• Management of functional dyspepsia
• Relief of nausea and vomiting episodes
• Treatment of delayed gastric emptying
• Alleviation of postprandial fullness and bloating
Vomistop effectively addresses these gastrointestinal symptoms by optimizing digestive tract motility.

How to Use

For optimal therapeutic outcomes:
1. Administer orally with water
2. Preferably take 15-30 minutes before meals
3. Adhere strictly to prescribed dosing schedule
4. Do not crush or chew tablets
5. Maintain consistent timing between doses
Always follow your healthcare provider’s specific instructions regarding dosage and duration of therapy.

How it Works

Vomistop’s active component, domperidone, functions as:
• A selective dopamine D2 receptor antagonist
• A gastrointestinal prokinetic agent
• A chemoreceptor trigger zone inhibitor
This triple-action mechanism enhances esophageal sphincter tone, accelerates gastric emptying, and coordinates antroduodenal motility while preventing nausea-inducing signals.

Benefits

Therapeutic advantages include:
✓ Rapid relief from upper GI symptoms
✓ Improved gastric emptying capacity
✓ Reduced postprandial discomfort
✓ Enhanced quality of life for patients with chronic dyspepsia
✓ Minimal central nervous system penetration (reduced risk of extrapyramidal effects)

Common Side Effects

While generally well-tolerated, some patients may experience:
• Mild headache (10-15% incidence)
• Transient dry mouth (5-8%)
• Occasional abdominal cramps (3-5%)
• Rare cases of diarrhea (2-3%)
These typically resolve with continued use. Report persistent or severe reactions to your physician.

Dosage and Administration

Standard dosing guidelines:
• Adults: 10 mg 3-4 times daily (max 30 mg/day)
• Pediatric (>12 years): 0.25 mg/kg per dose
• Elderly: Initiate with lower doses
• Renal impairment: Dose adjustment required
Always complete the prescribed course unless advised otherwise by your healthcare provider.

Warnings

Important safety considerations:
■ Contraindicated in patients with:
– Known hypersensitivity
– Prolactin-releasing pituitary tumors
– Severe hepatic impairment
■ Use caution with:
– Cardiac conditions (monitor ECG)
– Electrolyte imbalances
– Concurrent CYP3A4 inhibitors
■ Discontinue if signs of cardiac arrhythmias appear

Storage

Proper storage conditions:
• Temperature: 15-30°C (59-86°F)
• Humidity: <60% RH • Protection: Keep in original blister packaging • Shelf life: 24 months from manufacture date • Disposal: Return unused medication to pharmacy Maintain in child-resistant containers away from direct light and heat sources.