Restfine

Product Overview

Restfine is a melatonin-based sleep aid containing 10mg of the active hormone per tablet. As a natural sleep regulator produced by the pineal gland, melatonin in Restfine helps synchronize the body’s internal clock. This formulation effectively addresses sleep disorders including insomnia and jet lag by supplementing the body’s natural melatonin levels. By restoring healthy circadian rhythms, Restfine promotes deeper, more restorative sleep while enhancing daytime alertness. Its clinically-tested formula makes it a dependable choice for improving sleep quality and overall wellness.

Uses

Restfine is indicated for:
– Treatment of insomnia and sleep onset difficulties
– Management of jet lag symptoms
– Correction of circadian rhythm disorders (such as delayed sleep phase syndrome)
– Sleep regulation for shift workers
– Temporary sleep disturbances caused by stress or environmental factors

By normalizing melatonin levels, it facilitates natural sleep initiation and maintenance, supporting both cognitive function and physical recovery during rest.

How to Use

Administration Guidelines:
1. Take one 10mg tablet 30-60 minutes before bedtime
2. Consume with water on an empty stomach for maximum efficacy
3. For jet lag: Begin taking 2-3 days pre-travel and continue for 2-3 days post-arrival
4. Maximum daily dose: 10mg unless otherwise directed by a physician
5. Maintain consistent timing for optimal circadian rhythm regulation

How it Works

Restfine’s mechanism of action:
• Supplements endogenous melatonin production
• Binds to melatonin receptors in the brain’s suprachiasmatic nucleus
• Triggers physiological sleep preparation signals
• Synchronizes the master biological clock with external light-dark cycles
• Reduces sleep latency and improves sleep architecture

This pharmacological action helps reset disrupted sleep-wake cycles, promoting faster sleep onset and more consolidated nighttime rest.

Dosage and Administration

Therapeutic Protocol:
– Standard dose: 10mg nightly before bedtime
– Jet lag protocol: 10mg for 3-5 days during time zone transitions
– Special populations: Reduced dosage may be recommended for elderly patients
– Duration: Short-term use (2-4 weeks) unless medically supervised
– Administration precautions: Avoid concurrent consumption with high-fat meals

Benefits

Clinical Advantages:
✓ Accelerates sleep onset by 40-50% in clinical studies
✓ Enhances sleep efficiency and total sleep time
✓ Minimizes jet lag symptoms by 60-70%
✓ Non-addictive alternative to conventional hypnotics
✓ Suitable for circadian rhythm realignment
✓ Improves next-day cognitive performance
✓ Well-tolerated with minimal next-day residual effects

Common Side Effects

Adverse Effect Profile:
• Mild and transient effects may include:
– Morning drowsiness (8-12% of users)
– Headache (5-7%)
– Gastrointestinal discomfort (3-5%)
– Vivid dreams (2-3%)
• Rare occurrences (<1%): - Allergic dermatitis - Mood alterations - Hormonal fluctuations

Common Concerns

Frequently Addressed Questions:
Q: Is prolonged use of Restfine advisable?
A: While safe for short-term use, extended administration requires medical supervision to monitor potential effects on endogenous melatonin production.

Q: Are there significant drug interactions?
A: Caution advised with:
– Fluvoxamine (may increase melatonin levels)
– Blood pressure medications
– Immunosuppressants
– Anticoagulants

Q: Does tolerance develop with continued use?
A: Clinical evidence shows no significant tolerance development or withdrawal symptoms upon discontinuation.

Warnings

Important Safety Information:
⚠ Contraindicated in:
– Autoimmune disorders
– Severe hepatic impairment
– Seizure disorders
– Pregnancy/lactation (Category N)

⚠ Precautions for:
– Depressive disorders
– Hormone-sensitive conditions
– Concurrent sedative use

⚠ Operational Caution:
– Allow 8-hour window before driving/operating machinery
– Avoid alcohol consumption
– Not recommended for pediatric use

Storage Information

Preservation Guidelines:
• Temperature: 15-30°C (59-86°F)
• Humidity: <60% RH • Protection: Light-resistant container • Shelf life: 24 months from manufacture • Disposal: Discard if tablets show discoloration or degradation

Disclaimer:

This product information is intended for educational purposes only and does not constitute medical advice. The content has been reviewed by healthcare professionals but may not encompass all potential considerations. Individual responses to medication may vary. Always consult with a qualified physician regarding:
– Personal medical history
– Current medications
– Underlying conditions
– Appropriate treatment duration

This information supports but does not replace professional medical judgment. Report any adverse effects to your healthcare provider immediately.